Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00395817" target="_blank" >RIV/61389013:_____/13:00395817 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/13:00395817

Výsledek na webu

<a href="http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2642779/summary.html?type=number_search" target="_blank" >http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2642779/summary.html?type=number_search</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application

Popis výsledku v původním jazyce

The invention concerns superparamagnetic nanoparticle probes based on iron oxides with modified surface, method of their preparation and application. The probe is modified on its surface by a modification agent selected from the group consisting of mono-, di- and polysaccharides, poly(amino acid)s and polymers of (meth)acrylic acid derivatives, and form a colloid consisting of particles with narrow size distribution with polydispersity index lower than 1.3, the average size of which ranges from 10 to 30nm, iron oxide content amounts to 70-99.9 wt.%, the modification agent content makes 0.1-30 wt.%. The probes can be used for labelling cells used in magnetic resonance imaging for monitoring their movement, localization, survival and differentiation especially in detection of pathologies with cell dysfunction and of tissue regeneration and also for labelling and monitoring cells administered for cell therapy purposes in the recipient organism by magnetic resonance.

Název v anglickém jazyce

Superparamagnetic nanoparticles based on iron oxides with modified surface, method of their preparation and application

Popis výsledku anglicky

The invention concerns superparamagnetic nanoparticle probes based on iron oxides with modified surface, method of their preparation and application. The probe is modified on its surface by a modification agent selected from the group consisting of mono-, di- and polysaccharides, poly(amino acid)s and polymers of (meth)acrylic acid derivatives, and form a colloid consisting of particles with narrow size distribution with polydispersity index lower than 1.3, the average size of which ranges from 10 to 30nm, iron oxide content amounts to 70-99.9 wt.%, the modification agent content makes 0.1-30 wt.%. The probes can be used for labelling cells used in magnetic resonance imaging for monitoring their movement, localization, survival and differentiation especially in detection of pathologies with cell dysfunction and of tissue regeneration and also for labelling and monitoring cells administered for cell therapy purposes in the recipient organism by magnetic resonance.

Druh

P - Patent

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Číslo patentu nebo vzoru

CA2642779

Vydavatel

CA001 -

Název vydavatele

Canadian Intellectual Property Office (CIPO)

Místo vydání

Gatineau, Québec

Stát vydání

CA - Kanada

Datum přijetí

14. 5. 2013

Název vlastníka

Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i

Způsob využití

A - Výsledek využívá pouze poskytovatel

Druh možnosti využití

A - K využití výsledku jiným subjektem je vždy nutné nabytí licence