Tuning of polymeric nanoparticles by coassembly of thermoresponsive polymers and a double hydrophilic thermoresponsive block copolymer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F16%3A00460133" target="_blank" >RIV/61389013:_____/16:00460133 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1021/acs.jpcb.6b03414" target="_blank" >http://dx.doi.org/10.1021/acs.jpcb.6b03414</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.jpcb.6b03414" target="_blank" >10.1021/acs.jpcb.6b03414</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tuning of polymeric nanoparticles by coassembly of thermoresponsive polymers and a double hydrophilic thermoresponsive block copolymer

Popis výsledku v původním jazyce

The coassembly behavior of thermoresponsive statistical copolymers and a double hydrophilic block copolymer having a permanently hydrophilic block and a thermoresponsive block is investigated. By adjusting the hydrophilicity of the thermoresponsive statistical copolymers, hybrid nanoparticles are obtained with various ratios of the two species. Importantly, the size of these nanoparticles can be controlled in between 40 and 250 nm dependent on the TCP and the amount of statistical copolymers in the solution. Simultaneous analysis of static and dynamic light scattering data indicates that the possible structure of nanoparticles varies from hard sphere to less compact architecture and most probably depends on a difference between cloud point temperatures of individual components. This developed coassembly method provides a simple platform for the preparation of defined polymeric nanoparticles.

Název v anglickém jazyce

Tuning of polymeric nanoparticles by coassembly of thermoresponsive polymers and a double hydrophilic thermoresponsive block copolymer

Popis výsledku anglicky

The coassembly behavior of thermoresponsive statistical copolymers and a double hydrophilic block copolymer having a permanently hydrophilic block and a thermoresponsive block is investigated. By adjusting the hydrophilicity of the thermoresponsive statistical copolymers, hybrid nanoparticles are obtained with various ratios of the two species. Importantly, the size of these nanoparticles can be controlled in between 40 and 250 nm dependent on the TCP and the amount of statistical copolymers in the solution. Simultaneous analysis of static and dynamic light scattering data indicates that the possible structure of nanoparticles varies from hard sphere to less compact architecture and most probably depends on a difference between cloud point temperatures of individual components. This developed coassembly method provides a simple platform for the preparation of defined polymeric nanoparticles.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

—

Projekt

<a href="/cs/project/GC15-10527J" target="_blank" >GC15-10527J: Sférický „kůň ve vakuu“, anebo použitelné micely? Chování a tvar nanočástic – protirakovinných nosičů léčiv ve skutečném prostředí krve.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Physical Chemistry B

ISSN

1520-6106

e-ISSN

—

Svazek periodika

120

Číslo periodika v rámci svazku

20

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

4635-4643

Kód UT WoS článku

000376841300012

EID výsledku v databázi Scopus

2-s2.0-84973483797