Water soluble poly(styrene sulfonate)-b-poly(vinylidene fluoride)-b-poly(styrene sulfonate) triblock copolymer nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F16%3A00460137" target="_blank" >RIV/61389013:_____/16:00460137 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1039/C6RA10241G" target="_blank" >http://dx.doi.org/10.1039/C6RA10241G</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/C6RA10241G" target="_blank" >10.1039/C6RA10241G</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Water soluble poly(styrene sulfonate)-b-poly(vinylidene fluoride)-b-poly(styrene sulfonate) triblock copolymer nanoparticles

Popis výsledku v původním jazyce

A visible light, Mn2(CO)2-photomediated process was used to enable the iodine degenerative transfer controlled radical polymerization of vinylidene fluoride (VDF) initiated from I–(CF2)6–I, and the successive quantitative activation of the similar to CH2–CF2–I and silimar to CF2–CH2–I chain ends of I–PVDF–I, to produce a series of PNpSS-b-PVDF-b-PNpSS triblock copolymers (NpSS/VDF/NpSS = 4/60/4, 15/60/15, 34/60/34) with neopentyl styrene sulfonate (NpSS), which upon NaN3 deprotection, afforded the corresponding PNaSS-b-PVDF-b-PNaSS. All blocks, as well as PVDF, PNpSS and PNaSS formed water stable dispersion/solutions following either nanoprecipitation from acetone (PVDF, PNpSS, and PNpSS-b-PVDF-b-PNpSS) or direct dissolution in water (PNaSS, PNaSS-b-PVDF-b-PNaSS). Remarkably, all PNaSS-b-PVDF-b-PNaSS triblocks also provided indefinitely stable systems even under the high ionic strength conditions of phosphate buffered saline (PBS) solutions, corresponding to cell-isotonic, pH = 7.4 conditions. These trends were found to be consistent with the block composition dependence of the apparent hydrodynamic radius (Rh), conductivity, and zeta potential (ζ), where Rh increases upon deprotection from about 35–25 nm to about 168–136 nm in water, and decreases to 133–86 nm in PBS solutions, ζ decreases from similar to 40 mV to similar to 70 mV in water and increases to similar to 18 mV in PBS, and where the conductivity is negligible for PNpSS-b-PVDF-b-PNpSS but then increases linearly to similar to similar to 0.2 mS cm1 for PNaSS-b-PVDF-b-PNaSS in water to reach similar to 17 mS cm1 in PBS. Finally, the blocks were evaluated as promising 19F-MRI contrast agents.

Název v anglickém jazyce

Water soluble poly(styrene sulfonate)-b-poly(vinylidene fluoride)-b-poly(styrene sulfonate) triblock copolymer nanoparticles

Popis výsledku anglicky

A visible light, Mn2(CO)2-photomediated process was used to enable the iodine degenerative transfer controlled radical polymerization of vinylidene fluoride (VDF) initiated from I–(CF2)6–I, and the successive quantitative activation of the similar to CH2–CF2–I and silimar to CF2–CH2–I chain ends of I–PVDF–I, to produce a series of PNpSS-b-PVDF-b-PNpSS triblock copolymers (NpSS/VDF/NpSS = 4/60/4, 15/60/15, 34/60/34) with neopentyl styrene sulfonate (NpSS), which upon NaN3 deprotection, afforded the corresponding PNaSS-b-PVDF-b-PNaSS. All blocks, as well as PVDF, PNpSS and PNaSS formed water stable dispersion/solutions following either nanoprecipitation from acetone (PVDF, PNpSS, and PNpSS-b-PVDF-b-PNpSS) or direct dissolution in water (PNaSS, PNaSS-b-PVDF-b-PNaSS). Remarkably, all PNaSS-b-PVDF-b-PNaSS triblocks also provided indefinitely stable systems even under the high ionic strength conditions of phosphate buffered saline (PBS) solutions, corresponding to cell-isotonic, pH = 7.4 conditions. These trends were found to be consistent with the block composition dependence of the apparent hydrodynamic radius (Rh), conductivity, and zeta potential (ζ), where Rh increases upon deprotection from about 35–25 nm to about 168–136 nm in water, and decreases to 133–86 nm in PBS solutions, ζ decreases from similar to 40 mV to similar to 70 mV in water and increases to similar to 18 mV in PBS, and where the conductivity is negligible for PNpSS-b-PVDF-b-PNpSS but then increases linearly to similar to similar to 0.2 mS cm1 for PNaSS-b-PVDF-b-PNaSS in water to reach similar to 17 mS cm1 in PBS. Finally, the blocks were evaluated as promising 19F-MRI contrast agents.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

—

Projekt

<a href="/cs/project/LH14038" target="_blank" >LH14038: Fluorované polymerní systémy pro aplikace v palivových článcích</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

RSC Advances

ISSN

2046-2069

e-ISSN

—

Svazek periodika

6

Číslo periodika v rámci svazku

60

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

55374-55381

Kód UT WoS článku

000378274800089

EID výsledku v databázi Scopus

2-s2.0-84974605050