The manifold varieties of poly(2-hydroxyethyl methacrylate) hydrogels-IPNs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F17%3A00474506" target="_blank" >RIV/61389013:_____/17:00474506 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/masy.201700018" target="_blank" >http://dx.doi.org/10.1002/masy.201700018</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/masy.201700018" target="_blank" >10.1002/masy.201700018</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The manifold varieties of poly(2-hydroxyethyl methacrylate) hydrogels-IPNs

Popis výsledku v původním jazyce

The interpenetrating network structure was used to control mechanical properties of hydrogels based on poly(2-hydroxyethyl methacrylate) (PHEMA) (first network (A) or second network (B)) and poly(glycerol methacrylate) (PGMA) (network B). In order to understand the structure, mechanical and swelling properties of sequentially made IPN hydrogels, the swollen PHEMA network microstructure and its formation was investigated by means of swelling and SWAXS experiments. Visually clear and microscopically homogenous hydrogel networks based on poly(2-hydroxyethyl methacrylate) revealed presence of domains of size 1–10 nm formed during polymerization in the presence of water. The study was carried out to understand conditions under which the hydrophobic interactions are operative and their effect on the microstructure as well as how they change when the double network structure is introduced. The morphologies of network A ranged from homogenous, non-porous, and optically clear gels, to macroporous gels resulting from phase separation and offering fused-sphere morphology. A cryogel characterized by large elongated and partially interconnected pores of tens to hundreds micrometers were another object for comparison. In most cases, an increase of tensile moduli and improvement of ultimate tensile properties was achieved. A surprisingly high increase in true strength (by a factor of 10 – 30) was achieved when the macroporous PHEMA network A was reinforced by weak PHEMA or PGMA networks B. All these weakly crosslinked IPN gels were optically clear.

Název v anglickém jazyce

The manifold varieties of poly(2-hydroxyethyl methacrylate) hydrogels-IPNs

Popis výsledku anglicky

The interpenetrating network structure was used to control mechanical properties of hydrogels based on poly(2-hydroxyethyl methacrylate) (PHEMA) (first network (A) or second network (B)) and poly(glycerol methacrylate) (PGMA) (network B). In order to understand the structure, mechanical and swelling properties of sequentially made IPN hydrogels, the swollen PHEMA network microstructure and its formation was investigated by means of swelling and SWAXS experiments. Visually clear and microscopically homogenous hydrogel networks based on poly(2-hydroxyethyl methacrylate) revealed presence of domains of size 1–10 nm formed during polymerization in the presence of water. The study was carried out to understand conditions under which the hydrophobic interactions are operative and their effect on the microstructure as well as how they change when the double network structure is introduced. The morphologies of network A ranged from homogenous, non-porous, and optically clear gels, to macroporous gels resulting from phase separation and offering fused-sphere morphology. A cryogel characterized by large elongated and partially interconnected pores of tens to hundreds micrometers were another object for comparison. In most cases, an increase of tensile moduli and improvement of ultimate tensile properties was achieved. A surprisingly high increase in true strength (by a factor of 10 – 30) was achieved when the macroporous PHEMA network A was reinforced by weak PHEMA or PGMA networks B. All these weakly crosslinked IPN gels were optically clear.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/GA13-00939S" target="_blank" >GA13-00939S: Léčba chronického míšního poranění pomocí kmenových buněk a enzymů v kombinaci s polymerními nosiči</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Macromolecular Symposia. Volume 372, Issue 1

ISBN

—

ISSN

1022-1360

e-ISSN

1521-3900

Počet stran výsledku

15

Strana od-do

28-42

Název nakladatele

WILEY-VCH Verlag

Místo vydání

Weinheim

Místo konání akce

Stockholm

Datum konání akce

19. 6. 2016

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000399683500003