Heat generation of surface-modified magnetic .gamma.-Fe2O3 nanoparticles in applied alternating magnetic field

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F17%3A00477376" target="_blank" >RIV/61389013:_____/17:00477376 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1088/1361-6463/aa7bcb" target="_blank" >http://dx.doi.org/10.1088/1361-6463/aa7bcb</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/1361-6463/aa7bcb" target="_blank" >10.1088/1361-6463/aa7bcb</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Heat generation of surface-modified magnetic .gamma.-Fe2O3 nanoparticles in applied alternating magnetic field

Popis výsledku v původním jazyce

In this report, we show preparation of colloidally stable poly(N,N-dimethylacrylamide-coacrylic acid) (DMA)- and D-mannose (MAN)-coated maghemite nanoparticles and their ability to generate heat in an alternating magnetic field, which could make the particles applicable for hyperthermic therapy of cancer. The particles are obtained by coprecipitation reaction and characterized by transmission electron microscopy, dynamic light scattering, and AC calorimetric measurement of heat generated by the particles. While the dry particles were ca. 10 nm in diameter, their hydrodynamic size in water was within the range of 100 nm. Heating characteristics were measured in an LC circuit with a maximum field intensity of 6.8 kA . m(-1) and frequency 190 kHz. The specific absorption rates of gamma-Fe2O3, PDM@gamma-Fe2O3, and MAN@gamma-Fe2O3 nanoparticles were extrapolated to 10 kA . m(-1), reaching about 15 W . g(-1).

Název v anglickém jazyce

Heat generation of surface-modified magnetic .gamma.-Fe2O3 nanoparticles in applied alternating magnetic field

Popis výsledku anglicky

In this report, we show preparation of colloidally stable poly(N,N-dimethylacrylamide-coacrylic acid) (DMA)- and D-mannose (MAN)-coated maghemite nanoparticles and their ability to generate heat in an alternating magnetic field, which could make the particles applicable for hyperthermic therapy of cancer. The particles are obtained by coprecipitation reaction and characterized by transmission electron microscopy, dynamic light scattering, and AC calorimetric measurement of heat generated by the particles. While the dry particles were ca. 10 nm in diameter, their hydrodynamic size in water was within the range of 100 nm. Heating characteristics were measured in an LC circuit with a maximum field intensity of 6.8 kA . m(-1) and frequency 190 kHz. The specific absorption rates of gamma-Fe2O3, PDM@gamma-Fe2O3, and MAN@gamma-Fe2O3 nanoparticles were extrapolated to 10 kA . m(-1), reaching about 15 W . g(-1).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/GC16-01128J" target="_blank" >GC16-01128J: Magnetické nanočástice s antioxidačním účinkem na bázi přírodních antioxidantů: Interakce nanočástic s buňkami</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Physics D-Applied Physics

ISSN

0022-3727

e-ISSN

—

Svazek periodika

50

Číslo periodika v rámci svazku

34

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

1-6

Kód UT WoS článku

000407276500001

EID výsledku v databázi Scopus

2-s2.0-85027279528