Embedding of bacterial cellulose nanofibers within PHEMA hydrogel matrices: tunable stiffness composites with potential for biomedical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F18%3A00485031" target="_blank" >RIV/61389013:_____/18:00485031 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1155/2018/5217095" target="_blank" >http://dx.doi.org/10.1155/2018/5217095</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2018/5217095" target="_blank" >10.1155/2018/5217095</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Embedding of bacterial cellulose nanofibers within PHEMA hydrogel matrices: tunable stiffness composites with potential for biomedical applications

Popis výsledku v původním jazyce

Bacterial cellulose (BC) and poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels are both considered as biocompatible materials with potential use in various biomedical applications including cartilage, cardiovascular stent, and soft tissue engineering. In this work, the “ever-wet” process based on in situ UV radical polymerization of HEMA monomer in BC nanofibrous structure impregnated with HEMA was used, and a series of BC-PHEMA composites was prepared. The composite structures were characterized by ATR FT-IR spectroscopy, WAXD, SEM, and TEM techniques. The strategy of using densified BC material of various cellulose fiber contents was applied to improve mechanical properties. The mechanical properties were tested under tensile, dynamic shear, and relaxation modes. The final composites contained 1 to 20 wt% of BC. The effect of the reinforcement degree on morphology, swelling capacity, and mechanical properties was investigated. The biocompatibility test of BC-PHEMA composites was performed using mouse mesenchymal stem cells.

Název v anglickém jazyce

Embedding of bacterial cellulose nanofibers within PHEMA hydrogel matrices: tunable stiffness composites with potential for biomedical applications

Popis výsledku anglicky

Bacterial cellulose (BC) and poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels are both considered as biocompatible materials with potential use in various biomedical applications including cartilage, cardiovascular stent, and soft tissue engineering. In this work, the “ever-wet” process based on in situ UV radical polymerization of HEMA monomer in BC nanofibrous structure impregnated with HEMA was used, and a series of BC-PHEMA composites was prepared. The composite structures were characterized by ATR FT-IR spectroscopy, WAXD, SEM, and TEM techniques. The strategy of using densified BC material of various cellulose fiber contents was applied to improve mechanical properties. The mechanical properties were tested under tensile, dynamic shear, and relaxation modes. The final composites contained 1 to 20 wt% of BC. The effect of the reinforcement degree on morphology, swelling capacity, and mechanical properties was investigated. The biocompatibility test of BC-PHEMA composites was performed using mouse mesenchymal stem cells.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Nanomaterials

ISSN

1687-4110

e-ISSN

—

Svazek periodika

2018

Číslo periodika v rámci svazku

17 January

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

1-11

Kód UT WoS článku

000423585300001

EID výsledku v databázi Scopus

2-s2.0-85045932693