Synthesis and self-assembly of a carborane-containing ABC triblock terpolymer: morphology control on a dual-stimuli responsive system

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F19%3A00505383" target="_blank" >RIV/61389013:_____/19:00505383 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/19:10403391 RIV/00216208:11310/19:10403391

Výsledek na webu

<a href="https://pubs.rsc.org/en/content/articlelanding/2019/PY/C9PY00518H#!divAbstract" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2019/PY/C9PY00518H#!divAbstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c9py00518h" target="_blank" >10.1039/c9py00518h</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis and self-assembly of a carborane-containing ABC triblock terpolymer: morphology control on a dual-stimuli responsive system

Popis výsledku v původním jazyce

Amphiphilic triblock terpolymers have attractive applications in the preparation of nanoparticles with controlled morphology. An additional level of morphology control can be provided by reactive blocks, whose interactions with the solvent vary under different stimuli. In this work, we synthesized a triblock terpolymer (poly(acrylic acid)-b-poly(4-hydroxystyrene)-b-poly{1-[4-(1-methyl-1,2-dicarba-closo-dodecaborane-2-yl methyl)-phenyl]ethylene}) (PAA-b-PHS-b-PSC) containing carboranes as pendant groups by reversible addition fragmentation chain transfer (RAFT) polymerization and subsequently studied its behavior in aqueous solution. Once the nanoparticles were formed, the solubility of the second and third blocks was changed via pH and CsF reactions, respectively. The resulting micelles work as an ON/OFF system, using changes in fluorescence intensity at different pH values.

Název v anglickém jazyce

Synthesis and self-assembly of a carborane-containing ABC triblock terpolymer: morphology control on a dual-stimuli responsive system

Popis výsledku anglicky

Amphiphilic triblock terpolymers have attractive applications in the preparation of nanoparticles with controlled morphology. An additional level of morphology control can be provided by reactive blocks, whose interactions with the solvent vary under different stimuli. In this work, we synthesized a triblock terpolymer (poly(acrylic acid)-b-poly(4-hydroxystyrene)-b-poly{1-[4-(1-methyl-1,2-dicarba-closo-dodecaborane-2-yl methyl)-phenyl]ethylene}) (PAA-b-PHS-b-PSC) containing carboranes as pendant groups by reversible addition fragmentation chain transfer (RAFT) polymerization and subsequently studied its behavior in aqueous solution. Once the nanoparticles were formed, the solubility of the second and third blocks was changed via pH and CsF reactions, respectively. The resulting micelles work as an ON/OFF system, using changes in fluorescence intensity at different pH values.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/GJ17-00289Y" target="_blank" >GJ17-00289Y: Multikompartmentalizované nanostruktury citlivé na sacharidy a pH pro duální solubilizaci a uvolňování léčiv</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polymer Chemistry

ISSN

1759-9954

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

22

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

2774-2780

Kód UT WoS článku

000470708700002

EID výsledku v databázi Scopus

2-s2.0-85066941572