Biocompatible and antibacterial gelatin-based polypyrrole cryogels

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F20%3A00524035" target="_blank" >RIV/61389013:_____/20:00524035 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28110/20:63526480 RIV/70883521:28610/20:63526480

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0032386120303232?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0032386120303232?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.polymer.2020.122491" target="_blank" >10.1016/j.polymer.2020.122491</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Biocompatible and antibacterial gelatin-based polypyrrole cryogels

Popis výsledku v původním jazyce

Polypyrrole-gelatin cryogels were synthesized by oxidative cryopolymerization of pyrrole in the presence of gelatin. Vibrational spectroscopy confirmed formation of doped polypyrrole. Mechanical and pore structure stability of the resulting macroporous materials (pore size 10–50 μm) was shown to increase with increasing of gelatin content in initial polymerization medium, reaching plateau at 6 wt%. Thermal stability of polypyrrole-gelatin cryogels was found to be enhanced in comparison to its individual components. Electrical conductivity of all prepared cryogels (2–5 S cm−1) was similar to that of conventional polypyrrole. Cytotoxicity of polypyrrole-gelatin cryogels was found to decrease with increasing of gelatin concentration in the initial reaction mixture. The cryogel obtained using 8 wt% of gelatin showed the lowest cytotoxic effect reaching only mild cytotoxicity at 100% extract concentration. Polypyrrole-gelatin gels showed significant level of antibacterial activity without additional antibacterial agents.

Název v anglickém jazyce

Biocompatible and antibacterial gelatin-based polypyrrole cryogels

Popis výsledku anglicky

Polypyrrole-gelatin cryogels were synthesized by oxidative cryopolymerization of pyrrole in the presence of gelatin. Vibrational spectroscopy confirmed formation of doped polypyrrole. Mechanical and pore structure stability of the resulting macroporous materials (pore size 10–50 μm) was shown to increase with increasing of gelatin content in initial polymerization medium, reaching plateau at 6 wt%. Thermal stability of polypyrrole-gelatin cryogels was found to be enhanced in comparison to its individual components. Electrical conductivity of all prepared cryogels (2–5 S cm−1) was similar to that of conventional polypyrrole. Cytotoxicity of polypyrrole-gelatin cryogels was found to decrease with increasing of gelatin concentration in the initial reaction mixture. The cryogel obtained using 8 wt% of gelatin showed the lowest cytotoxic effect reaching only mild cytotoxicity at 100% extract concentration. Polypyrrole-gelatin gels showed significant level of antibacterial activity without additional antibacterial agents.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polymer

ISSN

0032-3861

e-ISSN

—

Svazek periodika

197

Číslo periodika v rámci svazku

27 May

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

1-7

Kód UT WoS článku

000533634800007

EID výsledku v databázi Scopus

2-s2.0-85083761680