Glass ionomer cement modified by a imidazolium salt: adding antifungal properties to a biomaterial

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00544228" target="_blank" >RIV/61389013:_____/21:00544228 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs42770-021-00511-5" target="_blank" >https://link.springer.com/article/10.1007%2Fs42770-021-00511-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s42770-021-00511-5" target="_blank" >10.1007/s42770-021-00511-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Glass ionomer cement modified by a imidazolium salt: adding antifungal properties to a biomaterial

Popis výsledku v původním jazyce

We present the structural modification of a commercially available glass ionomer cement by inserting the imidazolium salt 1-n-hexadecyl-3-methylimidazolium chloride (C16MImCl), composing a new biomaterial with antifungal biofilm activity. Test specimens were prepared using a commercial glass ionomer cement to which 10 ppm of cetylpyridinium chloride (reference ionic antifungal agent) or C16MImCl were added. The feasibility and hypoallergenicity of the new biomaterial were assessed by microhardness plastic deformation and chorioallantoic membrane assays. Colony counting and scanning electron microscopy were used to evaluate the modified specimens’ antibiofilm activity against three multidrug-resistant Candida species. The modified glass ionomer cement presented a strong antibiofilm activity against Candida spp., without losing its original micromechanical and hypoallergenic properties, rendering it a promising candidate for further application in dentistry.

Název v anglickém jazyce

Glass ionomer cement modified by a imidazolium salt: adding antifungal properties to a biomaterial

Popis výsledku anglicky

We present the structural modification of a commercially available glass ionomer cement by inserting the imidazolium salt 1-n-hexadecyl-3-methylimidazolium chloride (C16MImCl), composing a new biomaterial with antifungal biofilm activity. Test specimens were prepared using a commercial glass ionomer cement to which 10 ppm of cetylpyridinium chloride (reference ionic antifungal agent) or C16MImCl were added. The feasibility and hypoallergenicity of the new biomaterial were assessed by microhardness plastic deformation and chorioallantoic membrane assays. Colony counting and scanning electron microscopy were used to evaluate the modified specimens’ antibiofilm activity against three multidrug-resistant Candida species. The modified glass ionomer cement presented a strong antibiofilm activity against Candida spp., without losing its original micromechanical and hypoallergenic properties, rendering it a promising candidate for further application in dentistry.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Brazilian Journal of Microbiology

ISSN

1517-8382

e-ISSN

1678-4405

Svazek periodika

52

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

BR - Brazilská federativní republika

Počet stran výsledku

6

Strana od-do

1347-1352

Kód UT WoS článku

000647499500001

EID výsledku v databázi Scopus

2-s2.0-85105654614