Pomalejší růst nádorů z buněk melanomu B16 exponovaných fokusovanými rázovými vlnami

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F07%3A00096581" target="_blank" >RIV/61389021:_____/07:00096581 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389021:_____/07:00084236

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Reduced growth rate of tumors from melanoma B16 cells exposed to focused shock waves

Popis výsledku v původním jazyce

We have developed a generator of two successive shock waves focused to a common focal point. Amplitude of the pressure waves reaches up to 100 MPa at the focus and the rarefaction waves of 25 MPa in amplitude produce cavitations. Schlieren photography ofthe focal region has demonstrated that interaction of the two successive shocks results in creation of a very complex pressure field at the focus and in creation of many secondary spherical short wavelength shocks originated in collapsing cavitations. Measurements of waveforms by the PVDF shock gauges at the focus indicated that the second wave is strongly attenuated with the increasing time delay between the shocks. Suspension of the melanoma cells B16 has been exposed to 150 and 600 of focused shockwaves. Afterwards the cells have been inoculated to the inbred mice C57B16. Volume of the tumors growing from the exposed cells has been compared for 50 days with the tumors growing from the non exposed cells.

Název v anglickém jazyce

Reduced growth rate of tumors from melanoma B16 cells exposed to focused shock waves

Popis výsledku anglicky

We have developed a generator of two successive shock waves focused to a common focal point. Amplitude of the pressure waves reaches up to 100 MPa at the focus and the rarefaction waves of 25 MPa in amplitude produce cavitations. Schlieren photography ofthe focal region has demonstrated that interaction of the two successive shocks results in creation of a very complex pressure field at the focus and in creation of many secondary spherical short wavelength shocks originated in collapsing cavitations. Measurements of waveforms by the PVDF shock gauges at the focus indicated that the second wave is strongly attenuated with the increasing time delay between the shocks. Suspension of the melanoma cells B16 has been exposed to 150 and 600 of focused shockwaves. Afterwards the cells have been inoculated to the inbred mice C57B16. Volume of the tumors growing from the exposed cells has been compared for 50 days with the tumors growing from the non exposed cells.

Druh

D - Stať ve sborníku

CEP obor

BL - Fyzika plasmatu a výboje v plynech

OECD FORD obor

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Projekt

<a href="/cs/project/GA202%2F05%2F0685" target="_blank" >GA202/05/0685: Vzájemná interakce dvou rázových vln fokusovaných do společného ohniska</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 27th International Power Modulators Symposium and 2006 High Voltage workshops

ISBN

1-4244-0018-X

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

494-497

Název nakladatele

IEEE

Místo vydání

Piscataway

Místo konání akce

Washington, DC

Datum konání akce

15. 5. 2006

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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