Tandem shock waves in medicine and biology: a review of potential applications and successes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F16%3A00459233" target="_blank" >RIV/61389021:_____/16:00459233 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00193-015-0577-0" target="_blank" >http://dx.doi.org/10.1007/s00193-015-0577-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00193-015-0577-0" target="_blank" >10.1007/s00193-015-0577-0</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tandem shock waves in medicine and biology: a review of potential applications and successes

Popis výsledku v původním jazyce

Shock waves have been established as a safe and effective treatment for a wide range of diseases. Research groups worldwide are working on improving shock wave technology and developing new applications of shock waves to medicine and biology. The passage of a shock wave through soft tissue, fluids, and suspensions containing cells may result in acoustic cavitation i. e., the expansion and violent collapse of microbubbles, which generates secondary shock waves and the emission of microjets of fluid. Cavitation has been recognized as a significant phenomenon that produces both desirable and undesirable biomedical effects. Several studies have shown that cavitation can be controlled by emitting two shock waves that can be delayed by tenths or hundreds of microseconds. These dual-pulse pressure pulses, which are known as tandem shock waves, have been shown to enhance in vitro and in vivo urinary stone fragmentation, cause significant cytotoxic effects in tumor cells, delay tumor growth, enhance the bactericidal effect of shock waves and significantly increase the efficiency of genetic transformations in bacteria and fungi. This article provides an overview of the basic physical principles, methodologies, achievements and potential uses of tandem shock waves to improve biomedical applications.

Název v anglickém jazyce

Tandem shock waves in medicine and biology: a review of potential applications and successes

Popis výsledku anglicky

Shock waves have been established as a safe and effective treatment for a wide range of diseases. Research groups worldwide are working on improving shock wave technology and developing new applications of shock waves to medicine and biology. The passage of a shock wave through soft tissue, fluids, and suspensions containing cells may result in acoustic cavitation i. e., the expansion and violent collapse of microbubbles, which generates secondary shock waves and the emission of microjets of fluid. Cavitation has been recognized as a significant phenomenon that produces both desirable and undesirable biomedical effects. Several studies have shown that cavitation can be controlled by emitting two shock waves that can be delayed by tenths or hundreds of microseconds. These dual-pulse pressure pulses, which are known as tandem shock waves, have been shown to enhance in vitro and in vivo urinary stone fragmentation, cause significant cytotoxic effects in tumor cells, delay tumor growth, enhance the bactericidal effect of shock waves and significantly increase the efficiency of genetic transformations in bacteria and fungi. This article provides an overview of the basic physical principles, methodologies, achievements and potential uses of tandem shock waves to improve biomedical applications.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BL - Fyzika plasmatu a výboje v plynech

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Shock Waves

ISSN

0938-1287

e-ISSN

—

Svazek periodika

26

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

23

Strana od-do

1-23

Kód UT WoS článku

000372904900001

EID výsledku v databázi Scopus

2-s2.0-84954382451