Effect of artemisia absinthium and malva sylvestris on antioxidant parameters and abomasal histopathology in lambs experimentally infected with haemonchus contortus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F21%3A00545867" target="_blank" >RIV/61389030:_____/21:00545867 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/21:85610

Výsledek na webu

<a href="http://doi.org/10.3390/ani11020462" target="_blank" >http://doi.org/10.3390/ani11020462</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ani11020462" target="_blank" >10.3390/ani11020462</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of artemisia absinthium and malva sylvestris on antioxidant parameters and abomasal histopathology in lambs experimentally infected with haemonchus contortus

Popis výsledku v původním jazyce

This study evaluated the effect of Artemisia absinthium and Malva sylvestris on antioxidant response and histopathological changes in the abomasa of the Haemonchus contortus infected lambs. Twenty‐four lambs were divided into four groups: unsupplemented lambs (UNS), lambs supplemented with A. absinthium (ART), lambs supplemented with M. sylvestris (MAL), and lambs supplemented with both plants (ARTMAL). Lambs were infected orally with approximately 5000 thirdstage (L3) larvae of H. contortus. The experiment was conducted for 75 d (days), all animals were then slaughtered and the abomasal tissues were examined for antioxidant parameters and histopathology. The concentration of malondialdehyde in the abomasal mucosa was lower in ARTMAL (p < 0.05), and the total antioxidant capacity was higher in MAL (p < 0.05), than in UNS. Increased mucus production was observed in the ARTMAL. The number of mast cells in UNS and ART was significantly higher than the number in MAL (p < 0.01 and p < 0.05). Plasma cell numbers were higher in ARTMAL than the number in MAL (p < 0.05). Abomasal tissue regenerated more frequently in ARTMAL. These results represent the first report of the impact of A. absinthium and M. sylvestris on antioxidant parameters and local immune responses of abomasal mucosa of lambs infected with a GIN parasite.

Název v anglickém jazyce

Effect of artemisia absinthium and malva sylvestris on antioxidant parameters and abomasal histopathology in lambs experimentally infected with haemonchus contortus

Popis výsledku anglicky

This study evaluated the effect of Artemisia absinthium and Malva sylvestris on antioxidant response and histopathological changes in the abomasa of the Haemonchus contortus infected lambs. Twenty‐four lambs were divided into four groups: unsupplemented lambs (UNS), lambs supplemented with A. absinthium (ART), lambs supplemented with M. sylvestris (MAL), and lambs supplemented with both plants (ARTMAL). Lambs were infected orally with approximately 5000 thirdstage (L3) larvae of H. contortus. The experiment was conducted for 75 d (days), all animals were then slaughtered and the abomasal tissues were examined for antioxidant parameters and histopathology. The concentration of malondialdehyde in the abomasal mucosa was lower in ARTMAL (p < 0.05), and the total antioxidant capacity was higher in MAL (p < 0.05), than in UNS. Increased mucus production was observed in the ARTMAL. The number of mast cells in UNS and ART was significantly higher than the number in MAL (p < 0.01 and p < 0.05). Plasma cell numbers were higher in ARTMAL than the number in MAL (p < 0.05). Abomasal tissue regenerated more frequently in ARTMAL. These results represent the first report of the impact of A. absinthium and M. sylvestris on antioxidant parameters and local immune responses of abomasal mucosa of lambs infected with a GIN parasite.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40201 - Animal and dairy science; (Animal biotechnology to be 4.4)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Animals

ISSN

2076-2615

e-ISSN

2076-2615

Svazek periodika

11

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

13

Strana od-do

462

Kód UT WoS článku

000622072800001

EID výsledku v databázi Scopus

2-s2.0-85100588301