Analytical methods for the determination of neuroactive steroids

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F21%3A00546749" target="_blank" >RIV/61389030:_____/21:00546749 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/21:73606661

Výsledek na webu

<a href="http://doi.org/10.3390/biom11040553" target="_blank" >http://doi.org/10.3390/biom11040553</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/biom11040553" target="_blank" >10.3390/biom11040553</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Analytical methods for the determination of neuroactive steroids

Popis výsledku v původním jazyce

Neuroactive steroids are a family of all steroid‐based compounds, of both natural and synthetic origin, which can affect the nervous system functions. Their biosynthesis occurs directly in the nervous system (so‐called neurosteroids) or in peripheral endocrine tissues (hormonal ster-oids). Steroid hormone levels may fluctuate due to physiological changes during life and various pathological conditions affecting individuals. A deeper understanding of neuroactive steroids’ pro-duction, in addition to reliable monitoring of their levels in various biological matrices, may be use-ful in the prevention, diagnosis, monitoring, and treatment of some neurodegenerative and psychi-atric diseases. The aim of this review is to highlight the most relevant methods currently available for analysis of neuroactive steroids, with an emphasis on immunoanalytical methods and gas, or liquid chromatography combined with mass spectrometry.

Název v anglickém jazyce

Analytical methods for the determination of neuroactive steroids

Popis výsledku anglicky

Neuroactive steroids are a family of all steroid‐based compounds, of both natural and synthetic origin, which can affect the nervous system functions. Their biosynthesis occurs directly in the nervous system (so‐called neurosteroids) or in peripheral endocrine tissues (hormonal ster-oids). Steroid hormone levels may fluctuate due to physiological changes during life and various pathological conditions affecting individuals. A deeper understanding of neuroactive steroids’ pro-duction, in addition to reliable monitoring of their levels in various biological matrices, may be use-ful in the prevention, diagnosis, monitoring, and treatment of some neurodegenerative and psychi-atric diseases. The aim of this review is to highlight the most relevant methods currently available for analysis of neuroactive steroids, with an emphasis on immunoanalytical methods and gas, or liquid chromatography combined with mass spectrometry.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

<a href="/cs/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Rostliny jako prostředek udržitelného globálního rozvoje</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomolecules

ISSN

2218-273X

e-ISSN

2218-273X

Svazek periodika

11

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

23

Strana od-do

553

Kód UT WoS článku

000642792200001

EID výsledku v databázi Scopus

2-s2.0-85103816846