Simple Fabrication of Polycaprolactone-co-lactide Membrane with Silver Nanowires: Synthesis, Characterization and Cytotoxicity Studies

Kód výsledku v IS VaVaI

RIV/61389030:_____/22:00564954 - isvavai.cz

Nalezeny alternativní kódy

RIV/61989100:27230/22:10250789 RIV/61989100:27740/22:10250789 RIV/61989100:27360/22:10250789 RIV/61989100:27640/22:10250789 a 4 dalších

Výsledek na webu

https://doi.org/10.1007/s12221-022-4994-2

DOI - Digital Object Identifier

10.1007/s12221-022-4994-2

Jazyk výsledku

angličtina

Název v původním jazyce

Simple Fabrication of Polycaprolactone-co-lactide Membrane with Silver Nanowires: Synthesis, Characterization and Cytotoxicity Studies

Popis výsledku v původním jazyce

Our simple technique of polymer/metal-based material preparation produces very promising material, and we outline that this material can be suitable for the potential wound healing multilayered dressing. In our research we focused on these main issues: (1) the preparation of silver nanowire-like structures using gallic acid (GA), (2) direct silver nanowire-like structure crystallization of co-polymer L-lactide and ε-caprolactone (PLCL) electrospun fiber and (3) evaluation of the material cytotoxicity on the Vero cell line. Synthesized silver nanowire-like width varied from 30 to 100 nm and the hexagonal particles had sizes from 80 to 300 nm. The detected structures were crystalline cubic silver and were similarly synthesized during both batch synthesis and direct synthesis on the PLCL fibers. The amount of the silver spread within the fibrous membrane was approximately 1.1 wt. % in the sample, moreover, the silver incorporation had no influence on the polymer structure, which was confirmed by FTIR measurement. The cytotoxicity testing estimated that cell survival increased with decreased concentration of GA and silver in the PLCL matrix and the silver-based sample in 50 % MTT extraction concentration maintained required non-cytotoxic properties.

Název v anglickém jazyce

Simple Fabrication of Polycaprolactone-co-lactide Membrane with Silver Nanowires: Synthesis, Characterization and Cytotoxicity Studies

Popis výsledku anglicky

Our simple technique of polymer/metal-based material preparation produces very promising material, and we outline that this material can be suitable for the potential wound healing multilayered dressing. In our research we focused on these main issues: (1) the preparation of silver nanowire-like structures using gallic acid (GA), (2) direct silver nanowire-like structure crystallization of co-polymer L-lactide and ε-caprolactone (PLCL) electrospun fiber and (3) evaluation of the material cytotoxicity on the Vero cell line. Synthesized silver nanowire-like width varied from 30 to 100 nm and the hexagonal particles had sizes from 80 to 300 nm. The detected structures were crystalline cubic silver and were similarly synthesized during both batch synthesis and direct synthesis on the PLCL fibers. The amount of the silver spread within the fibrous membrane was approximately 1.1 wt. % in the sample, moreover, the silver incorporation had no influence on the polymer structure, which was confirmed by FTIR measurement. The cytotoxicity testing estimated that cell survival increased with decreased concentration of GA and silver in the PLCL matrix and the silver-based sample in 50 % MTT extraction concentration maintained required non-cytotoxic properties.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Fibers and Polymers

ISSN

1229-9197

e-ISSN

1875-0052

Svazek periodika

23

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

2983-2993

Kód UT WoS článku

000885028000001

EID výsledku v databázi Scopus

2-s2.0-85142253058