Recent advances in nanomaterial-based optical biosensors and their biomedical and biopharmaceutical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F26%3A00647369" target="_blank" >RIV/61389030:_____/26:00647369 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.jpha.2025.101349" target="_blank" >https://doi.org/10.1016/j.jpha.2025.101349</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jpha.2025.101349" target="_blank" >10.1016/j.jpha.2025.101349</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Recent advances in nanomaterial-based optical biosensors and their biomedical and biopharmaceutical applications

Popis výsledku v původním jazyce

Optical biosensors are gaining popularity owing to their portability, miniaturization, no requirement for additional attachments, and rapid responsiveness. These features render them suitable for various applications including at-home diagnostics, pharmacology, and continuous molecular monitoring. The integration of functionalized low-dimensional nanomaterials (zero-dimensional (0D), 1D, 2D, and 3D) has redirected focus towards the design, fabrication, and optimization of optical biosensors. This review summarizes the fundamental mechanisms underlying optical biosensing. The key mechanisms include localized surface plasmon resonance (LSPR), photoluminescence (PL), surface enhancement Raman scattering (SERS), nanozyme-based colorimetric strategies, chemiluminescence, bioluminescence, and electrochemiluminescence. The advantages of various low-dimensional nanomaterials for different types of optical biosensors are presented. This comparison emphasizes their potential superiority in targeted biosensing applications. Therefore, promoting optical biosensing techniques and recent developments in advanced biosensing strategies for biomedical research and biopharmaceutical applications are necessary to establish their future directions.

Název v anglickém jazyce

Recent advances in nanomaterial-based optical biosensors and their biomedical and biopharmaceutical applications

Popis výsledku anglicky

Optical biosensors are gaining popularity owing to their portability, miniaturization, no requirement for additional attachments, and rapid responsiveness. These features render them suitable for various applications including at-home diagnostics, pharmacology, and continuous molecular monitoring. The integration of functionalized low-dimensional nanomaterials (zero-dimensional (0D), 1D, 2D, and 3D) has redirected focus towards the design, fabrication, and optimization of optical biosensors. This review summarizes the fundamental mechanisms underlying optical biosensing. The key mechanisms include localized surface plasmon resonance (LSPR), photoluminescence (PL), surface enhancement Raman scattering (SERS), nanozyme-based colorimetric strategies, chemiluminescence, bioluminescence, and electrochemiluminescence. The advantages of various low-dimensional nanomaterials for different types of optical biosensors are presented. This comparison emphasizes their potential superiority in targeted biosensing applications. Therefore, promoting optical biosensing techniques and recent developments in advanced biosensing strategies for biomedical research and biopharmaceutical applications are necessary to establish their future directions.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

<a href="/cs/project/GA23-05389S" target="_blank" >GA23-05389S: Nové CB2 a BChE modulátory proti Parkinsonově chorobě a souvisejícím patologiím</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2026

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Pharmaceutical Analysis

ISSN

2095-1779

e-ISSN

2214-0883

Svazek periodika

16

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

22

Strana od-do

101349

Kód UT WoS článku

001674686800001

EID výsledku v databázi Scopus

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