Are changes in heart rate variability in middle-aged and older people normative or due to pathological conditions? Findings from a large population-based longitudinal cohort study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F16%3AA1701F9Z" target="_blank" >RIV/61988987:17110/16:A1701F9Z - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Are changes in heart rate variability in middle-aged and older people normative or due to pathological conditions? Findings from a large population-based longitudinal cohort study

Popis výsledku v původním jazyce

No study to date has investigated longitudinal trajectories of cardiac autonomic modulation changes with aging; therefore, we lack evidence showing whether these changes occur naturally or are secondary to disease or medication use. This study tested whether heart rate variability (HRV) trajectories from middle to older age are largely normative or caused by pathological changes with aging in a large prospective cohort. We further assessed whether HRV changes were modified by socioeconomic status, ethnicity, or habitual physical activity. This study involved 3176 men and 1238 women initially aged 44 to 69 years (1997-1999) from the UK Whitehall II population?based cohort. We evaluated time? and frequency?domain HRV measures of short?term recordings at 3 time points over a 10?year period. Random mixed models with time?varying covariates were applied. Cross?sectionally, HRV measures were lower for men than for women, for participants with cardiometabolic conditions, and for participants reporting

Název v anglickém jazyce

Are changes in heart rate variability in middle-aged and older people normative or due to pathological conditions? Findings from a large population-based longitudinal cohort study

Popis výsledku anglicky

No study to date has investigated longitudinal trajectories of cardiac autonomic modulation changes with aging; therefore, we lack evidence showing whether these changes occur naturally or are secondary to disease or medication use. This study tested whether heart rate variability (HRV) trajectories from middle to older age are largely normative or caused by pathological changes with aging in a large prospective cohort. We further assessed whether HRV changes were modified by socioeconomic status, ethnicity, or habitual physical activity. This study involved 3176 men and 1238 women initially aged 44 to 69 years (1997-1999) from the UK Whitehall II population?based cohort. We evaluated time? and frequency?domain HRV measures of short?term recordings at 3 time points over a 10?year period. Random mixed models with time?varying covariates were applied. Cross?sectionally, HRV measures were lower for men than for women, for participants with cardiometabolic conditions, and for participants reporting

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

—

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of American Heart Association

ISSN

2047-9980

e-ISSN

—

Svazek periodika

feb 2016

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

1-13

Kód UT WoS článku

000378131100024

EID výsledku v databázi Scopus

—