Thoughts on anaesthesia in chronobiological studies with electrocardiograms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F16%3AA1701J7D" target="_blank" >RIV/61988987:17110/16:A1701J7D - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Thoughts on anaesthesia in chronobiological studies with electrocardiograms

Popis výsledku v původním jazyce

Pentobarbital, ketamine/xylazine and zoletil are the most commonly used agents for general anaesthesia in experimental studies using animal models. Table 1 summarizes the results of our chronobiological studies investigating the impact of anaesthesia on cardiac electrophysiology in rats. The results clearly show differences among three types of anaesthetics and their effects on the circadian rhythmicity of myocardial electrophysiological parameters in an in vivo rat model, presented in our studies as ?light-dark differences?. Although studies from other groups (Ohno et al. 2009, Mihara et al. 2012) have reported moderate or, alternatively, no effects of pentobarbital on the circadian rhythm of locomotor activity and the secretion of specific hormones in mice and rats, the disruptive effect of pentobarbital on circadian oscillations in electrophysiological parameters of the rat heart was evident in our study.

Název v anglickém jazyce

Thoughts on anaesthesia in chronobiological studies with electrocardiograms

Popis výsledku anglicky

Pentobarbital, ketamine/xylazine and zoletil are the most commonly used agents for general anaesthesia in experimental studies using animal models. Table 1 summarizes the results of our chronobiological studies investigating the impact of anaesthesia on cardiac electrophysiology in rats. The results clearly show differences among three types of anaesthetics and their effects on the circadian rhythmicity of myocardial electrophysiological parameters in an in vivo rat model, presented in our studies as ?light-dark differences?. Although studies from other groups (Ohno et al. 2009, Mihara et al. 2012) have reported moderate or, alternatively, no effects of pentobarbital on the circadian rhythm of locomotor activity and the secretion of specific hormones in mice and rats, the disruptive effect of pentobarbital on circadian oscillations in electrophysiological parameters of the rat heart was evident in our study.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

AN - Psychologie

OECD FORD obor

—

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ACTA PHYSIOLOGICA

ISSN

1748-1708

e-ISSN

—

Svazek periodika

218

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

2

Strana od-do

71-72

Kód UT WoS článku

000383576900004

EID výsledku v databázi Scopus

—