Erratum to: Per-oral endoscopic myotomy (POEM): mid-term efficacy and safety

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA1801PDR" target="_blank" >RIV/61988987:17110/17:A1801PDR - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00464-017-5828-y" target="_blank" >http://dx.doi.org/10.1007/s00464-017-5828-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00464-017-5828-y" target="_blank" >10.1007/s00464-017-5828-y</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Erratum to: Per-oral endoscopic myotomy (POEM): mid-term efficacy and safety

Popis výsledku v původním jazyce

Per-oral endoscopic myotomy(POEM) is becoming a standard treatment for achalasia. Long-term efficacy and the rate of post-POEM refluxshould be further investigated. The main aim of this studywas to analyze safety and mid-term (12 and 24 months)clinical outcomes of POEM. Methods: Data on single tertiary center procedures werecollected prospectively. The primary outcome was treatmentsuccess defined as an Eckardt score < 3 at 12 and 24 months. A total of 155 consecutive patients withachalasia underwent POEM; 133 patients were includedinto the analysis (22 patients will be analyzed separately aspart of a multicenter randomized clinical trial).Results POEM was successfully completed in 132 (99.2%)patients, and the mean length of the procedure was 69.8min (range 31-136). One patient underwent a drainagefor pleural effusion; no other serious adverse eventsoccurred. Treatment success at 3, 12, and 24 months wasobserved in 95.5% (CI 89.6-98.1), 93.4% (86.5-96.8), and84.0% (71.4-91.4) of patients, respectively. A total of 11patients (8.3%) reported initial treatment failure (n = 5) orlater recurrence (n = 6). The majority of relapses occurredin patients with achalasia type I (16.7 vs. 1.1% achalasiatype II vs. 0% achalasia type III; p < 0.05). At 12 months,post-POEM reflux symptoms were present in 29.7% ofpatients. At 3 months, mild reflux esophagitis was diagnosedin 37.6% of patients, and pathological gastroesophagealreflux was detected in 41.5% of patients. A totalof 37.8% of patients had been treated with a proton pumpinhibitor.Conclusion POEM resulted in greater than 90% treatmentsuccess at 12 months which tends to decrease to 84% after2 years. More than one-third of the patients had mild refluxsymptoms and/or mild esophagitis.

Název v anglickém jazyce

Erratum to: Per-oral endoscopic myotomy (POEM): mid-term efficacy and safety

Popis výsledku anglicky

Per-oral endoscopic myotomy(POEM) is becoming a standard treatment for achalasia. Long-term efficacy and the rate of post-POEM refluxshould be further investigated. The main aim of this studywas to analyze safety and mid-term (12 and 24 months)clinical outcomes of POEM. Methods: Data on single tertiary center procedures werecollected prospectively. The primary outcome was treatmentsuccess defined as an Eckardt score < 3 at 12 and 24 months. A total of 155 consecutive patients withachalasia underwent POEM; 133 patients were includedinto the analysis (22 patients will be analyzed separately aspart of a multicenter randomized clinical trial).Results POEM was successfully completed in 132 (99.2%)patients, and the mean length of the procedure was 69.8min (range 31-136). One patient underwent a drainagefor pleural effusion; no other serious adverse eventsoccurred. Treatment success at 3, 12, and 24 months wasobserved in 95.5% (CI 89.6-98.1), 93.4% (86.5-96.8), and84.0% (71.4-91.4) of patients, respectively. A total of 11patients (8.3%) reported initial treatment failure (n = 5) orlater recurrence (n = 6). The majority of relapses occurredin patients with achalasia type I (16.7 vs. 1.1% achalasiatype II vs. 0% achalasia type III; p < 0.05). At 12 months,post-POEM reflux symptoms were present in 29.7% ofpatients. At 3 months, mild reflux esophagitis was diagnosedin 37.6% of patients, and pathological gastroesophagealreflux was detected in 41.5% of patients. A totalof 37.8% of patients had been treated with a proton pumpinhibitor.Conclusion POEM resulted in greater than 90% treatmentsuccess at 12 months which tends to decrease to 84% after2 years. More than one-third of the patients had mild refluxsymptoms and/or mild esophagitis.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30218 - General and internal medicine

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Surgical Endoscopy and Other Interventional Techniques

ISSN

0930-2794

e-ISSN

—

Svazek periodika

—

Číslo periodika v rámci svazku

září

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

—

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85029108762