Role of confocal laser endomicroscopy in patients with early esophageal neoplasia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F18%3AA1901VW5" target="_blank" >RIV/61988987:17110/18:A1901VW5 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/18:10381812 RIV/00023001:_____/18:00077431

Výsledek na webu

<a href="http://dx.doi.org/10.23736/S0026-4733.18.07795-7" target="_blank" >http://dx.doi.org/10.23736/S0026-4733.18.07795-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0026-4733.18.07795-7" target="_blank" >10.23736/S0026-4733.18.07795-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Role of confocal laser endomicroscopy in patients with early esophageal neoplasia

Popis výsledku v původním jazyce

Probe-based confocal laser endomicroscopy (pCLE) enables real-time histopathological assessment during endoscopic procedures to evaluate epithelial and subepithelial structures with a 1000x magnification. It may be used in various localizations not only in the digestive tract, but its role in clinical practice is still a matter of discussion. The main advantages of pCLE compared to standard biopsies may be: 1) real-time diagnosis; 2) which may be done by the endoscopist; and 3) a larger evaluated area compared to standard biopsies. In theory, pCLE has the potential to eliminate the need for biopsy. However, pCLE cannot replace standard biopsies at this time, among others, standard forceps biopsies are presently more cost-effective. pCLE may be used to enhance the diagnostic arsenal and improve mucosal visualization and evaluation in patients with Barrett's esophagus (BE), with visible esophageal lesions and in patients undergoing surveillance endoscopy after endoscopic treatment of BE related neoplasia. pCLE requires sufficient training and use of validated classifications systems. At present, the majority of endoscopic centers do not use pCLE routinely and no guidelines recommend its routine use for patients with different esophageal diseases, although pCLE is (in selected indications) reimbursed in some countries. This article describes the principle and performance of pCLE and reviews its use in patients with BE and early esophageal neoplasia.

Název v anglickém jazyce

Role of confocal laser endomicroscopy in patients with early esophageal neoplasia

Popis výsledku anglicky

Probe-based confocal laser endomicroscopy (pCLE) enables real-time histopathological assessment during endoscopic procedures to evaluate epithelial and subepithelial structures with a 1000x magnification. It may be used in various localizations not only in the digestive tract, but its role in clinical practice is still a matter of discussion. The main advantages of pCLE compared to standard biopsies may be: 1) real-time diagnosis; 2) which may be done by the endoscopist; and 3) a larger evaluated area compared to standard biopsies. In theory, pCLE has the potential to eliminate the need for biopsy. However, pCLE cannot replace standard biopsies at this time, among others, standard forceps biopsies are presently more cost-effective. pCLE may be used to enhance the diagnostic arsenal and improve mucosal visualization and evaluation in patients with Barrett's esophagus (BE), with visible esophageal lesions and in patients undergoing surveillance endoscopy after endoscopic treatment of BE related neoplasia. pCLE requires sufficient training and use of validated classifications systems. At present, the majority of endoscopic centers do not use pCLE routinely and no guidelines recommend its routine use for patients with different esophageal diseases, although pCLE is (in selected indications) reimbursed in some countries. This article describes the principle and performance of pCLE and reviews its use in patients with BE and early esophageal neoplasia.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

<a href="/cs/project/NV16-27648A" target="_blank" >NV16-27648A: Probe-based konfokální laserová endomikroskopie v histopatologické diagnostice neoplastických lézí trávicího traktu</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MINERVA CHIRURGICA

ISSN

0026-4733

e-ISSN

1827-1626

Svazek periodika

73

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

11

Strana od-do

417-427

Kód UT WoS článku

000445223700008

EID výsledku v databázi Scopus

2-s2.0-85051108847