Advancement in liver laparoscopic resection - development of a new surgical device

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F18%3AA1901Z4G" target="_blank" >RIV/61988987:17110/18:A1901Z4G - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27230/18:10241345 RIV/00843989:_____/18:E0106997

Výsledek na webu

<a href="http://dx.doi.org/10.1590/1414-431X20176062" target="_blank" >http://dx.doi.org/10.1590/1414-431X20176062</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1590/1414-431X20176062" target="_blank" >10.1590/1414-431X20176062</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Advancement in liver laparoscopic resection - development of a new surgical device

Popis výsledku v původním jazyce

Liver resection is the standard treatment for any liver lesion. Laparoscopic liver resection is associated with lower intra-operative blood loss and fewer complications than open resection. Access to the posterior part of the right liver lobe is very uncomfortable and difficult for surgeons due the anatomic position, especially when employing laparoscopic surgery. Based on these experiences, a new laparoscopic device was developed that is capable of bending its long axis and allowing the application of radiofrequency energy in areas that were not technically accessible. The device is equipped with four telescopic needle electrodes that cause tissue coagulation after the delivery of radiofrequency energy. Ex vivo testing was performed in 2012 and 2014 at the University Hospital, Ostrava, on a porcine liver tissue. The main goal of this testing was to verify if the newly proposed electrode layout was suitable for sufficient tissue coagulation and creating a safety zone around lesions. During the ex vivo testing, the material of needle electrodes was improved to achieve the lowest possibility of adhesion. The power supply was adjusted from 20 to 120 W and the ablation time, which varied from 10 to 110 s, was monitored. Subsequently, optimal power delivery and time for coagulation was determined. This experimental study demonstrated the feasibility and safety of the newly developed device. Based on the ex vivo testing, LARA-K1 can create a safety zone of coagulation. For further assessment of the new device, an in vivo study should be performed.

Název v anglickém jazyce

Advancement in liver laparoscopic resection - development of a new surgical device

Popis výsledku anglicky

Liver resection is the standard treatment for any liver lesion. Laparoscopic liver resection is associated with lower intra-operative blood loss and fewer complications than open resection. Access to the posterior part of the right liver lobe is very uncomfortable and difficult for surgeons due the anatomic position, especially when employing laparoscopic surgery. Based on these experiences, a new laparoscopic device was developed that is capable of bending its long axis and allowing the application of radiofrequency energy in areas that were not technically accessible. The device is equipped with four telescopic needle electrodes that cause tissue coagulation after the delivery of radiofrequency energy. Ex vivo testing was performed in 2012 and 2014 at the University Hospital, Ostrava, on a porcine liver tissue. The main goal of this testing was to verify if the newly proposed electrode layout was suitable for sufficient tissue coagulation and creating a safety zone around lesions. During the ex vivo testing, the material of needle electrodes was improved to achieve the lowest possibility of adhesion. The power supply was adjusted from 20 to 120 W and the ablation time, which varied from 10 to 110 s, was monitored. Subsequently, optimal power delivery and time for coagulation was determined. This experimental study demonstrated the feasibility and safety of the newly developed device. Based on the ex vivo testing, LARA-K1 can create a safety zone of coagulation. For further assessment of the new device, an in vivo study should be performed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

ISSN

0100-879X

e-ISSN

1678-4510

Svazek periodika

4

Číslo periodika v rámci svazku

51

Stát vydavatele periodika

BR - Brazilská federativní republika

Počet stran výsledku

4

Strana od-do

1-4

Kód UT WoS článku

000426392900001

EID výsledku v databázi Scopus

2-s2.0-85043273535