THE EFFECT OF LONG-TERM VAGUS NERVE STIMULATION ON COGNITIVE FUNCTION: RANDOMIZED PLACEBO WAITLIST-CONTROLLED TRIAL (A STUDY PROTOCOL)

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

THE EFFECT OF LONG-TERM VAGUS NERVE STIMULATION ON COGNITIVE FUNCTION: RANDOMIZED PLACEBO WAITLIST-CONTROLLED TRIAL (A STUDY PROTOCOL)

Popis výsledku v původním jazyce

Cognitive health is generally considered a key component of quality of life. Current evidence indicates that a large number of individuals are at a high risk for cognitive impairment from many causes as they age. In order to preserve and enhance positive out-comes by targeted efficient preventive and therapeutic strategies it is important to understand potential mechanisms and predictors of cognitive health and impairment. Withdrawal of vagal (parasympathetic) activity has been proposed as one of the biological pathways involved in cognitive impairment. Transcutaneous vagus nerve stimulation (tVNS) has shown potential as a noninvasive and safe therapeutic treatment due to its direct influence on brain systems involved in cognition. However, the role of vagal modulation in cognitive functioning and impairment and the influence of tVNS, particularly long-term tVNS, on cognition are not yet completely understood. Here the investigators aim to investigate the effect of long-term (14days) intensive transcutaneous vagus nerve stimulation on cognitive functions in relatively healthy young-to-older adults.

Název v anglickém jazyce

THE EFFECT OF LONG-TERM VAGUS NERVE STIMULATION ON COGNITIVE FUNCTION: RANDOMIZED PLACEBO WAITLIST-CONTROLLED TRIAL (A STUDY PROTOCOL)

Popis výsledku anglicky

Cognitive health is generally considered a key component of quality of life. Current evidence indicates that a large number of individuals are at a high risk for cognitive impairment from many causes as they age. In order to preserve and enhance positive out-comes by targeted efficient preventive and therapeutic strategies it is important to understand potential mechanisms and predictors of cognitive health and impairment. Withdrawal of vagal (parasympathetic) activity has been proposed as one of the biological pathways involved in cognitive impairment. Transcutaneous vagus nerve stimulation (tVNS) has shown potential as a noninvasive and safe therapeutic treatment due to its direct influence on brain systems involved in cognition. However, the role of vagal modulation in cognitive functioning and impairment and the influence of tVNS, particularly long-term tVNS, on cognition are not yet completely understood. Here the investigators aim to investigate the effect of long-term (14days) intensive transcutaneous vagus nerve stimulation on cognitive functions in relatively healthy young-to-older adults.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Psychosomatic Medicine

ISBN

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ISSN

0033-3174

e-ISSN

1534-7796

Počet stran výsledku

1

Strana od-do

53-53

Název nakladatele

Lippincott Williams and Wilkins

Místo vydání

Philadelphia

Místo konání akce

Vancouver, Canada

Datum konání akce

6. 3. 2019

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000467560700151