MACROPHAGES OF THE SUBCUTANEOUS AND OMENTAL FATTY TISSUE IN OBESE PATIENTS: IMMUNOHISTOCHEMICAL PHENOTYPING OF M2 SUBTYPES IN RELATION TO TYPE 2 DIABETES

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F20%3AA210210I" target="_blank" >RIV/61988987:17110/20:A210210I - isvavai.cz</a>

Výsledek na webu

<a href="https://biomed.papers.upol.cz/pdfs/bio/2020/02/02.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2020/02/02.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2019.011" target="_blank" >10.5507/bp.2019.011</a>

Jazyk výsledku

angličtina

Název v původním jazyce

MACROPHAGES OF THE SUBCUTANEOUS AND OMENTAL FATTY TISSUE IN OBESE PATIENTS: IMMUNOHISTOCHEMICAL PHENOTYPING OF M2 SUBTYPES IN RELATION TO TYPE 2 DIABETES

Popis výsledku v původním jazyce

Macrophages are linked to the initiation of the chronic inflammation believed to underlie the changes taking place in the white fatty tissue of obese people. Both the number of macrophages, but their functional status, play an important role in the development of inflammation. Classically, macrophages are divided into two types: pro-inflammatory (M1) and anti-inflammatory (M2) types, and based on current immunological studies, further views on the functional distribution of macrophages are suggested. In this study, we evaluated the M1 and M2 macrophages ratio in obese subjects with, or without diabetes. To identify all macrophages, we used CD68 expression, while CD204 expression is typically used for the M2 macrophage.

Název v anglickém jazyce

MACROPHAGES OF THE SUBCUTANEOUS AND OMENTAL FATTY TISSUE IN OBESE PATIENTS: IMMUNOHISTOCHEMICAL PHENOTYPING OF M2 SUBTYPES IN RELATION TO TYPE 2 DIABETES

Popis výsledku anglicky

Macrophages are linked to the initiation of the chronic inflammation believed to underlie the changes taking place in the white fatty tissue of obese people. Both the number of macrophages, but their functional status, play an important role in the development of inflammation. Classically, macrophages are divided into two types: pro-inflammatory (M1) and anti-inflammatory (M2) types, and based on current immunological studies, further views on the functional distribution of macrophages are suggested. In this study, we evaluated the M1 and M2 macrophages ratio in obese subjects with, or without diabetes. To identify all macrophages, we used CD68 expression, while CD204 expression is typically used for the M2 macrophage.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30502 - Other medical science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS

ISSN

1213-8118

e-ISSN

1804-7521

Svazek periodika

164

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

133-137

Kód UT WoS článku

000542635800002

EID výsledku v databázi Scopus

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