Metal Particles in Mucus and Hypertrophic Tissue of the Inferior Nasal Turbinates From the Human Upper Respiratory Tract

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F20%3AA21025AL" target="_blank" >RIV/61988987:17110/20:A21025AL - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27240/20:10239435 RIV/61989100:27640/20:10239435 RIV/61989100:27690/20:10239435 RIV/00843989:_____/20:E0108479

Výsledek na webu

<a href="https://link.springer.com/content/pdf/10.1007/s11356-020-09156-7.pdf" target="_blank" >https://link.springer.com/content/pdf/10.1007/s11356-020-09156-7.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11356-020-09156-7" target="_blank" >10.1007/s11356-020-09156-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Metal Particles in Mucus and Hypertrophic Tissue of the Inferior Nasal Turbinates From the Human Upper Respiratory Tract

Popis výsledku v původním jazyce

Mucosal surfaces are the first mechanical barrier preventing the entry of foreign particles into the organism. The study addresses the detection and analysis of metal-based solid particles in cytological mucus samples from the surface of human hypertrophic tissue in the inferior nasal turbinates in patients diagnosed with chronic rhinitis. Solid particles were characterized by scanning electron microscopy and Raman microspectroscopy; all the biological samples were also subjected to vibration magnetometry. Since the upper airways are the first part of the respiratory tract, which is exposed to inhaled particles, it can be assumed that inhaled particles may be partially deposited in this region. Scanning electron microscopy revealed the presence of metal-based solid particles/clusters in the majority of the analysed cytological mucus samples and also in hypertrophic tissues; in all groups, the particles were of submicron size. Raman microspectroscopy detected the presence of particles/clusters based on amorphous carbon, graphite, calcium carbonate, anatase and barite only in the hypertrophic tissue. The obtained results show that the composition of some of the solid particles (i.e. Ba, Zn, Fe and Ti) detected in the mucus from the surface of the hypertrophic tissues resembled the particles found in the hypertrophic tissue itself. It can be assumed that after the capture of the inhaled particles by the mucus, they penetrate into the deeper layers of tissue.

Název v anglickém jazyce

Metal Particles in Mucus and Hypertrophic Tissue of the Inferior Nasal Turbinates From the Human Upper Respiratory Tract

Popis výsledku anglicky

Mucosal surfaces are the first mechanical barrier preventing the entry of foreign particles into the organism. The study addresses the detection and analysis of metal-based solid particles in cytological mucus samples from the surface of human hypertrophic tissue in the inferior nasal turbinates in patients diagnosed with chronic rhinitis. Solid particles were characterized by scanning electron microscopy and Raman microspectroscopy; all the biological samples were also subjected to vibration magnetometry. Since the upper airways are the first part of the respiratory tract, which is exposed to inhaled particles, it can be assumed that inhaled particles may be partially deposited in this region. Scanning electron microscopy revealed the presence of metal-based solid particles/clusters in the majority of the analysed cytological mucus samples and also in hypertrophic tissues; in all groups, the particles were of submicron size. Raman microspectroscopy detected the presence of particles/clusters based on amorphous carbon, graphite, calcium carbonate, anatase and barite only in the hypertrophic tissue. The obtained results show that the composition of some of the solid particles (i.e. Ba, Zn, Fe and Ti) detected in the mucus from the surface of the hypertrophic tissues resembled the particles found in the hypertrophic tissue itself. It can be assumed that after the capture of the inhaled particles by the mucus, they penetrate into the deeper layers of tissue.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10511 - Environmental sciences (social aspects to be 5.7)

Projekt

<a href="/cs/project/EF17_049%2F0008441" target="_blank" >EF17_049/0008441: Inovativní léčebné metody pohybového aparátu v úrazové chirurgii</a><br>

Návaznosti

O - Projekt operacniho programu

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

ISSN

0944-1344

e-ISSN

1614-7499

Svazek periodika

27

Číslo periodika v rámci svazku

22

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

9

Strana od-do

28146-28154

Kód UT WoS článku

000532905200003

EID výsledku v databázi Scopus

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