Estimated glomerular filtration rate in patients overdosed with gentamicin

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F20%3AA21025ZP" target="_blank" >RIV/61988987:17110/20:A21025ZP - isvavai.cz</a>

Výsledek na webu

<a href="https://www.degruyter.com/view/journals/labm/44/1/article-p35.xml" target="_blank" >https://www.degruyter.com/view/journals/labm/44/1/article-p35.xml</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/labmed-2019-0124" target="_blank" >10.1515/labmed-2019-0124</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Estimated glomerular filtration rate in patients overdosed with gentamicin

Popis výsledku v původním jazyce

Background: The aim of this study was to compare the estimated glomerular filtration rate (eGFR) from serum creatinine (eGFRcrea) and cystatin C (eGFRcys) in patients with elevated serum trough levels of gentamicin before the next planned dose during treatment in the intensive care unit (ICU). Methods: This was a retrospective observational study. Patients who stayed in an ICU, received a once-daily dose of gentamicin, and who had results from all serum gentamicin trough levels, eGFRcrea and eGFRcys analyses were included in the study. Overdosed patients were defined as those with serum gentamicin trough levels above 1 mg/L before the next dose. Gentamicin was measured by a particle-enhanced turbidimetric immunoassay (PETIA). Creatinine and cystatin C were measured by standardized methods.

Název v anglickém jazyce

Estimated glomerular filtration rate in patients overdosed with gentamicin

Popis výsledku anglicky

Background: The aim of this study was to compare the estimated glomerular filtration rate (eGFR) from serum creatinine (eGFRcrea) and cystatin C (eGFRcys) in patients with elevated serum trough levels of gentamicin before the next planned dose during treatment in the intensive care unit (ICU). Methods: This was a retrospective observational study. Patients who stayed in an ICU, received a once-daily dose of gentamicin, and who had results from all serum gentamicin trough levels, eGFRcrea and eGFRcys analyses were included in the study. Overdosed patients were defined as those with serum gentamicin trough levels above 1 mg/L before the next dose. Gentamicin was measured by a particle-enhanced turbidimetric immunoassay (PETIA). Creatinine and cystatin C were measured by standardized methods.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF LABORATORY MEDICINE

ISSN

2567-9430

e-ISSN

2567-9449

Svazek periodika

44

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

4

Strana od-do

35-39

Kód UT WoS článku

000512769200007

EID výsledku v databázi Scopus

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