Cardiovascular Risk Factors and DXA-Assessed Body Composition Changes after Laparoscopic Sleeve Gastrectomy: A One-Year Retrospective Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F25%3AA2603DNC" target="_blank" >RIV/61988987:17110/25:A2603DNC - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/25:00143018 RIV/00843989:_____/25:E0112058

Výsledek na webu

<a href="http://e-coretvasa.cz/doi/10.33678/cor.2025.020.html" target="_blank" >http://e-coretvasa.cz/doi/10.33678/cor.2025.020.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33678/cor.2025.020" target="_blank" >10.33678/cor.2025.020</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cardiovascular Risk Factors and DXA-Assessed Body Composition Changes after Laparoscopic Sleeve Gastrectomy: A One-Year Retrospective Study

Popis výsledku v původním jazyce

Background: While laparoscopic sleeve gastrectomy (LSG) is known to reduce weight, its impact on cardiovascular risk profile through changes in body composition remains unclear. Methods: This retrospective study evaluated 98 patients who underwent LSG, analyzing body composition via dual-energy X-ray absorptiometry (DXA) and cardiovascular risk parameters at baseline and 12 months post-surgery. Changes in weight, fat mass, lean mass, atherogenic lipid profile, and glucose metabolism were assessed, along with their interrelationships. Results: Significant reductions were observed in total body weight, fat mass, and lean mass at 12 months post-surgery (all p <0.001). Metabolic parameters showed marked improvements, with significant decreases in fasting glucose, HbA1c, and triglycerides, alongside an increase in HDL cholesterol (all p <0.001). The LDL/ HDL ratio improved from median (IQR) 2.79 (1.59) to 2.20 (0.91) (p <0.001). The atherogenic index of plasma decreased from 0.23 (0.30) to-0.10 (0.29) (p <0.001), representing a shift from increased to low cardiovascular risk. A moderate negative correlation was identified between changes in lean mass and HDL cholesterol (r = -0.331, p <0.001), while weak but significant correlations were found between changes in waist-to-hip ratio and glycemic parameters. Conclusions: LSG results in significant improvements in cardiovascular risk profile at one year post-surgery, with favorable changes in atherogenic lipid parameters and body composition. The novel correlation between lean mass preservation and HDL cholesterol suggests that maintaining muscle mass might be crucial for optimizing cardiovascular benefits following bariatric surgery.

Název v anglickém jazyce

Cardiovascular Risk Factors and DXA-Assessed Body Composition Changes after Laparoscopic Sleeve Gastrectomy: A One-Year Retrospective Study

Popis výsledku anglicky

Background: While laparoscopic sleeve gastrectomy (LSG) is known to reduce weight, its impact on cardiovascular risk profile through changes in body composition remains unclear. Methods: This retrospective study evaluated 98 patients who underwent LSG, analyzing body composition via dual-energy X-ray absorptiometry (DXA) and cardiovascular risk parameters at baseline and 12 months post-surgery. Changes in weight, fat mass, lean mass, atherogenic lipid profile, and glucose metabolism were assessed, along with their interrelationships. Results: Significant reductions were observed in total body weight, fat mass, and lean mass at 12 months post-surgery (all p <0.001). Metabolic parameters showed marked improvements, with significant decreases in fasting glucose, HbA1c, and triglycerides, alongside an increase in HDL cholesterol (all p <0.001). The LDL/ HDL ratio improved from median (IQR) 2.79 (1.59) to 2.20 (0.91) (p <0.001). The atherogenic index of plasma decreased from 0.23 (0.30) to-0.10 (0.29) (p <0.001), representing a shift from increased to low cardiovascular risk. A moderate negative correlation was identified between changes in lean mass and HDL cholesterol (r = -0.331, p <0.001), while weak but significant correlations were found between changes in waist-to-hip ratio and glycemic parameters. Conclusions: LSG results in significant improvements in cardiovascular risk profile at one year post-surgery, with favorable changes in atherogenic lipid parameters and body composition. The novel correlation between lean mass preservation and HDL cholesterol suggests that maintaining muscle mass might be crucial for optimizing cardiovascular benefits following bariatric surgery.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/NW24-09-00016" target="_blank" >NW24-09-00016: Prevence vzniku sarkopenie u pacientů po bariatricko-metabolických operacích: vliv programovaného aerobního a silového cvičení na funkčnost, objem a morfologii svalové tkáně</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cor et Vasa

ISSN

0010-8650

e-ISSN

1803-7712

Svazek periodika

—

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

555-560

Kód UT WoS článku

001618286800001

EID výsledku v databázi Scopus

2-s2.0-105023972843