A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F24%3AA25039QX" target="_blank" >RIV/61988987:17310/24:A25039QX - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064211:_____/24:W0000048

Výsledek na webu

<a href="https://dx.plos.org/10.1371/journal.pntd.0012767" target="_blank" >https://dx.plos.org/10.1371/journal.pntd.0012767</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pntd.0012767" target="_blank" >10.1371/journal.pntd.0012767</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus

Popis výsledku v původním jazyce

Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures of visceral organs.The disease is exacerbated if a parasite harbors Leishmania RNA viruses (LRVs) of thefamily Pseudototiviridae. Screening a novel isolate of L. braziliensis, we revealed that it possesses not a toti-, but a bunyavirus of the family Leishbuviridae. To the best of our knowledge, this is a very first discovery of a bunyavirus infecting a representative of theLeishmania subgenus Viannia. We suggest that these viruses may serve as potential factors of virulence in American leishmaniasis and encourage researchers to test leishmanialstrains for the presence of not only LRVs, but also other RNA viruses.

Název v anglickém jazyce

A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus

Popis výsledku anglicky

Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures of visceral organs.The disease is exacerbated if a parasite harbors Leishmania RNA viruses (LRVs) of thefamily Pseudototiviridae. Screening a novel isolate of L. braziliensis, we revealed that it possesses not a toti-, but a bunyavirus of the family Leishbuviridae. To the best of our knowledge, this is a very first discovery of a bunyavirus infecting a representative of theLeishmania subgenus Viannia. We suggest that these viruses may serve as potential factors of virulence in American leishmaniasis and encourage researchers to test leishmanialstrains for the presence of not only LRVs, but also other RNA viruses.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10607 - Virology

Projekt

<a href="/cs/project/GA24-10009S" target="_blank" >GA24-10009S: Viry trypanosomatid: údržba a přenos</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLOS NEGLECTED TROPICAL DISEASES

ISSN

1935-2735

e-ISSN

1935-2735

Svazek periodika

—

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

19

Strana od-do

—

Kód UT WoS článku

001385304100001

EID výsledku v databázi Scopus

2-s2.0-85215145367