Finite Element Analysis of Silver Nanorods, Spheres, Ellipsoids and Core-Shell Structures for Hyperthermia Treatment of Cancer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27230%2F22%3A10249927" target="_blank" >RIV/61989100:27230/22:10249927 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:000773874700001" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:000773874700001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ma15051786" target="_blank" >10.3390/ma15051786</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Finite Element Analysis of Silver Nanorods, Spheres, Ellipsoids and Core-Shell Structures for Hyperthermia Treatment of Cancer

Popis výsledku v původním jazyce

The finite element analysis technique was used to investigate the suitability of silver nanorods, spheres, ellipsoids and core-shell structures for the hyperthermia treatment of cancer. The temperature of the silver nanostructures was raised from 42 to 46 &amp; DEG;C, in order to kill the cancerous cells. The time taken by the nanostructures to attain this temperature, with external source heating, was also estimated. The heat transfer module in COMSOL Multiphysics was used for the finite element analysis of hyperthermia, based on silver nanostructures. The thermal response of different shapes of silver nanostructures was evaluated by placing them inside the spherical domain of the tumor tissue. The proposed geometries were heated at different time intervals. Optimization of the geometries was performed to achieve the best treatment temperature. It was observed that silver nanorods quickly attain the desired temperature, as compared to other shapes. The silver nanorods achieved the highest temperature of 44.3 &amp; DEG;C among all the analyzed geometries. Moreover, the central volume, used to identify the thermal response, was the maximum for the silver nano-ellipsoids. Thermal equilibrium in the treatment region was attained after 0.5 mu s of heating, which made these structures suitable for hyperthermia treatment.

Název v anglickém jazyce

Finite Element Analysis of Silver Nanorods, Spheres, Ellipsoids and Core-Shell Structures for Hyperthermia Treatment of Cancer

Popis výsledku anglicky

The finite element analysis technique was used to investigate the suitability of silver nanorods, spheres, ellipsoids and core-shell structures for the hyperthermia treatment of cancer. The temperature of the silver nanostructures was raised from 42 to 46 &amp; DEG;C, in order to kill the cancerous cells. The time taken by the nanostructures to attain this temperature, with external source heating, was also estimated. The heat transfer module in COMSOL Multiphysics was used for the finite element analysis of hyperthermia, based on silver nanostructures. The thermal response of different shapes of silver nanostructures was evaluated by placing them inside the spherical domain of the tumor tissue. The proposed geometries were heated at different time intervals. Optimization of the geometries was performed to achieve the best treatment temperature. It was observed that silver nanorods quickly attain the desired temperature, as compared to other shapes. The silver nanorods achieved the highest temperature of 44.3 &amp; DEG;C among all the analyzed geometries. Moreover, the central volume, used to identify the thermal response, was the maximum for the silver nano-ellipsoids. Thermal equilibrium in the treatment region was attained after 0.5 mu s of heating, which made these structures suitable for hyperthermia treatment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

<a href="/cs/project/EF17_049%2F0008407" target="_blank" >EF17_049/0008407: Inovativní a aditivní technologie výroby - nová technologická řešení 3D tisku kovů a kompozitních materiálů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials

ISSN

1996-1944

e-ISSN

1996-1944

Svazek periodika

15

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

13

Strana od-do

nestrankovano

Kód UT WoS článku

000773874700001

EID výsledku v databázi Scopus

2-s2.0-85125768567