Methodology for estimation of undeformed thickness of arterial tissues

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27230%2F23%3A10252614" target="_blank" >RIV/61989100:27230/23:10252614 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.nature.com/articles/s41598-023-28871-y" target="_blank" >https://www.nature.com/articles/s41598-023-28871-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-023-28871-y" target="_blank" >10.1038/s41598-023-28871-y</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Methodology for estimation of undeformed thickness of arterial tissues

Popis výsledku v původním jazyce

Soft tissue sample thickness measurement is one of the major sources of differences between mechanical responses published by different groups. New method for the estimation of unloaded sample thickness of soft tissues is proposed in this study. Ten 30 x 30 mm and ten 20 x 20 mm samples of porcine anterior thoracic aortas were loaded by gradually increased radial force. Their deformed thickness was then recorded in order to generate a pressure-thickness response. Next, the limit pressure to which the response can be considered linear was estimated. Line was fitted to the linear part of the curve and extrapolated towards zero pressure to estimate unloaded thickness (7 kPa fit). For comparison, data near zero pressure were fitted separately and extrapolated towards zero (Near Zero fit). The limit pressure for the linearity of the response was around 7 kPa. The Unloaded thickness for 30 x 30 mm samples was 2.68 +- 0.31 mm and 2.68 +- 0.3 mm for Near Zero fit and 7 kPa fit, respectively. The Unloaded thickness for 20 x 20 mm samples was 2.60 +- 0.35 mm and 2.59 +- 0.35 mm for Near Zero fit and 7 kPa fit, respectively. The median of thickness difference between smaller and larger samples was not found statistically different. Proposed method can estimate unloaded undeformed sample thickness quickly and reliably. (C) 2023, The Author(s).

Název v anglickém jazyce

Methodology for estimation of undeformed thickness of arterial tissues

Popis výsledku anglicky

Soft tissue sample thickness measurement is one of the major sources of differences between mechanical responses published by different groups. New method for the estimation of unloaded sample thickness of soft tissues is proposed in this study. Ten 30 x 30 mm and ten 20 x 20 mm samples of porcine anterior thoracic aortas were loaded by gradually increased radial force. Their deformed thickness was then recorded in order to generate a pressure-thickness response. Next, the limit pressure to which the response can be considered linear was estimated. Line was fitted to the linear part of the curve and extrapolated towards zero pressure to estimate unloaded thickness (7 kPa fit). For comparison, data near zero pressure were fitted separately and extrapolated towards zero (Near Zero fit). The limit pressure for the linearity of the response was around 7 kPa. The Unloaded thickness for 30 x 30 mm samples was 2.68 +- 0.31 mm and 2.68 +- 0.3 mm for Near Zero fit and 7 kPa fit, respectively. The Unloaded thickness for 20 x 20 mm samples was 2.60 +- 0.35 mm and 2.59 +- 0.35 mm for Near Zero fit and 7 kPa fit, respectively. The median of thickness difference between smaller and larger samples was not found statistically different. Proposed method can estimate unloaded undeformed sample thickness quickly and reliably. (C) 2023, The Author(s).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20600 - Medical engineering

Projekt

<a href="/cs/project/GJ19-22426Y" target="_blank" >GJ19-22426Y: Vliv patologií na tvar pulzní vlny v tepnách a jejich nízkocyklovou únavu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scientific Reports

ISSN

2045-2322

e-ISSN

2045-2322

Svazek periodika

13

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

—

Kód UT WoS článku

001003483300073

EID výsledku v databázi Scopus

2-s2.0-85148263103