Nanostructured Hemostatic Sponges Made from Chitosan: Structural and Biological Evaluation.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27350%2F20%3A10245080" target="_blank" >RIV/61989100:27350/20:10245080 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/chapter/10.1007/978-981-15-3996-1_10" target="_blank" >https://link.springer.com/chapter/10.1007/978-981-15-3996-1_10</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-15-3996-1_10" target="_blank" >10.1007/978-981-15-3996-1_10</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nanostructured Hemostatic Sponges Made from Chitosan: Structural and Biological Evaluation.

Popis výsledku v původním jazyce

Local hemostatic agents are a necessary element of surgical work that reduces blood loss and mortality. Despite the variety of materials, there is no perfect styptic. The most promising hemostatic agents are based on biomaterials therefore they can be left in the wound. The aim of the following research was to obtain a new type of biocompatible chitosan-based agents with high hemostatic activity. The biomaterials were obtained under microwave radiation using l-aspartic acid, l-glutamic acid as crosslinking agents. Chitosan sponges showed high porosity and antioxidant activity, and also high antibacterial activity against both S. aureus and to E. coli. This material was absolutely non-toxic on cell culture and showed good hemostatic properties after interaction with blood in vitro.

Název v anglickém jazyce

Nanostructured Hemostatic Sponges Made from Chitosan: Structural and Biological Evaluation.

Popis výsledku anglicky

Local hemostatic agents are a necessary element of surgical work that reduces blood loss and mortality. Despite the variety of materials, there is no perfect styptic. The most promising hemostatic agents are based on biomaterials therefore they can be left in the wound. The aim of the following research was to obtain a new type of biocompatible chitosan-based agents with high hemostatic activity. The biomaterials were obtained under microwave radiation using l-aspartic acid, l-glutamic acid as crosslinking agents. Chitosan sponges showed high porosity and antioxidant activity, and also high antibacterial activity against both S. aureus and to E. coli. This material was absolutely non-toxic on cell culture and showed good hemostatic properties after interaction with blood in vitro.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Nanomaterials in Biomedical Application and Biosensors (NAP- 2019)

ISBN

978-981-15-3995-4

Počet stran výsledku

15

Strana od-do

95-110

Počet stran knihy

271

Název nakladatele

Springer Nature Singapore Pte Ltd. 2020

Místo vydání

Singapore

Kód UT WoS kapitoly

—