Antimicrobial bionanocomposite-from precursors to the functional material in one simple step

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27360%2F16%3A86099169" target="_blank" >RIV/61989100:27360/16:86099169 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27640/16:86099169 RIV/61989100:27740/16:86099169

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11051-016-3664-y" target="_blank" >http://dx.doi.org/10.1007/s11051-016-3664-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11051-016-3664-y" target="_blank" >10.1007/s11051-016-3664-y</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antimicrobial bionanocomposite-from precursors to the functional material in one simple step

Popis výsledku v původním jazyce

The mesoporous biosilica with unique 3D hierarchy in/organic functional groups is attractive material in terms of interfacial phenomena, and its high biocompatibility accelerates development in biomedical devices. In addition, their benefits also play a fundamental role in antimicrobial assessment. We hypothesize that the Diadesmis gallica biosilica surface acts as a biotemplate for AgCl and Au nanoparticle (NP) biosynthesis. Moreover, it exhibits antibacterial action human pathogenic bacteria. Nanoparticle biosynthesis was performed via a pure environmental-friendly, static, bottom-up in vitro regime. Minimal inhibitory concentrations evaluated systems with bionanocomposites for antibacterial efficiency in temporal time-dose-dependency. TEM and XRD depicts a biosilica "local sphere" which affects formation, stabilization and encapsulation of crystalline Au (9-27 nm) and AgCl (3-51 nm) NPs in one simple step. FTIR analysis reveals various functional in/organic groups, including Si-OH and polyamides. While both metal-bionanoparticles have analogical spherical shape with determined aggregation, ICP-AES analysis determined more effective 5.29 wt% Au NP formation than 1 wt% AgCl NPs. MIC analysis confirms that bionanocomposite with AgCl by concentration 0.014 mg/mL has the most effective antibacterial system for gram-positive and gram-negative bacteria strains. Although dual effect of Au/AgCl NP bionanocomposite has almost analogical influence on gram-positive bacteria, the synergic-antagonistic effect is irrelevant in this instance.

Název v anglickém jazyce

Antimicrobial bionanocomposite-from precursors to the functional material in one simple step

Popis výsledku anglicky

The mesoporous biosilica with unique 3D hierarchy in/organic functional groups is attractive material in terms of interfacial phenomena, and its high biocompatibility accelerates development in biomedical devices. In addition, their benefits also play a fundamental role in antimicrobial assessment. We hypothesize that the Diadesmis gallica biosilica surface acts as a biotemplate for AgCl and Au nanoparticle (NP) biosynthesis. Moreover, it exhibits antibacterial action human pathogenic bacteria. Nanoparticle biosynthesis was performed via a pure environmental-friendly, static, bottom-up in vitro regime. Minimal inhibitory concentrations evaluated systems with bionanocomposites for antibacterial efficiency in temporal time-dose-dependency. TEM and XRD depicts a biosilica "local sphere" which affects formation, stabilization and encapsulation of crystalline Au (9-27 nm) and AgCl (3-51 nm) NPs in one simple step. FTIR analysis reveals various functional in/organic groups, including Si-OH and polyamides. While both metal-bionanoparticles have analogical spherical shape with determined aggregation, ICP-AES analysis determined more effective 5.29 wt% Au NP formation than 1 wt% AgCl NPs. MIC analysis confirms that bionanocomposite with AgCl by concentration 0.014 mg/mL has the most effective antibacterial system for gram-positive and gram-negative bacteria strains. Although dual effect of Au/AgCl NP bionanocomposite has almost analogical influence on gram-positive bacteria, the synergic-antagonistic effect is irrelevant in this instance.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JI - Kompositní materiály

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Nanoparticle Research

ISSN

1388-0764

e-ISSN

—

Svazek periodika

18

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

1-11

Kód UT WoS článku

000390056000002

EID výsledku v databázi Scopus

2-s2.0-85002263462