Preparation of antibacterial chlorhexidine/vermiculite and release study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F17%3A10237001" target="_blank" >RIV/61989100:27640/17:10237001 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27740/17:10237001 RIV/71009396:_____/17:N0000019

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0301751616302708" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0301751616302708</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.minpro.2016.12.002" target="_blank" >10.1016/j.minpro.2016.12.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Preparation of antibacterial chlorhexidine/vermiculite and release study

Popis výsledku v původním jazyce

The antibacterial chlorhexidine/vermiculite (CA/Ver) was successfully prepared through the intercalation process and the stability of CA on the vermiculite matrix and was investigated by stirring in aqueous solutions under the influence of different pH and temperature. The content of CA was determined by total organic carbon (TOC) analysis before and after stability tests. The structure of all samples was characterized by X-ray powder diffraction (XRD) and Fourier–transforminfrared spectroscopy (FTIR). The antibacterial activity of prepared CA/Ver samples was evaluated by finding a minimum inhibitory concentration (MIC) against Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. The content of chlorhexidine ranged from 209 to 231.6 mg of CA in 1 g of the whole sample after the intercalation process. After stability study, only a slight outflow of CA from the Ver matrix (5%) was noted. The antibacterial test confirmed that the outflow of CA was negligible. After 30min of exposition the MIC of organovermiculite samples before and after stability test were the same for Staphylococcus aureus and Escherichia coli with value 3.33 (%; w/v) and the MIC decreased to 0.014 (%; w/v) with longer time of exposition (120 h). A small difference was observed at Enterococcus faecalis where MIC was 10 (%; w/v) after 30 min of exposition for the sample after stability test in neutral pH. However, after 24 h of treatment the MIC value decreased to 0.014 (%; w/v). And finally, bacterial strain Pseudomonas aeruginosa showed a great resistance against antibacterial organovermiculite samples and MIC did not decreased under 10 (%; w/v) even after 5 days of exposition.

Název v anglickém jazyce

Preparation of antibacterial chlorhexidine/vermiculite and release study

Popis výsledku anglicky

The antibacterial chlorhexidine/vermiculite (CA/Ver) was successfully prepared through the intercalation process and the stability of CA on the vermiculite matrix and was investigated by stirring in aqueous solutions under the influence of different pH and temperature. The content of CA was determined by total organic carbon (TOC) analysis before and after stability tests. The structure of all samples was characterized by X-ray powder diffraction (XRD) and Fourier–transforminfrared spectroscopy (FTIR). The antibacterial activity of prepared CA/Ver samples was evaluated by finding a minimum inhibitory concentration (MIC) against Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. The content of chlorhexidine ranged from 209 to 231.6 mg of CA in 1 g of the whole sample after the intercalation process. After stability study, only a slight outflow of CA from the Ver matrix (5%) was noted. The antibacterial test confirmed that the outflow of CA was negligible. After 30min of exposition the MIC of organovermiculite samples before and after stability test were the same for Staphylococcus aureus and Escherichia coli with value 3.33 (%; w/v) and the MIC decreased to 0.014 (%; w/v) with longer time of exposition (120 h). A small difference was observed at Enterococcus faecalis where MIC was 10 (%; w/v) after 30 min of exposition for the sample after stability test in neutral pH. However, after 24 h of treatment the MIC value decreased to 0.014 (%; w/v). And finally, bacterial strain Pseudomonas aeruginosa showed a great resistance against antibacterial organovermiculite samples and MIC did not decreased under 10 (%; w/v) even after 5 days of exposition.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

Projekt

<a href="/cs/project/GAP210%2F11%2F2215" target="_blank" >GAP210/11/2215: Studium a hodnocení struktur vermikulitů modifikovaných ve funkci nanoplniv a podložek</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Mineral Processing

ISSN

0301-7516

e-ISSN

—

Svazek periodika

159

Číslo periodika v rámci svazku

8 December 2016

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

1-6

Kód UT WoS článku

000393720300001

EID výsledku v databázi Scopus

2-s2.0-85007089921