Prognostické faktory pro přežití pacientů s nehodgkinskými lymphomy (NHL) po autologní transplantaci krvetvorných buněk - nezávislá zkušenost centra

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F06%3A00002731" target="_blank" >RIV/61989592:15110/06:00002731 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience

Popis výsledku v původním jazyce

Several prognostic factors had been previously reported to be associated with overall and progression-free survival of patients with NHL after APSCT. We present a retrospective single center analysis with special attention to the markers that reflect theactivity of disease at the time of transplantation. 122 patients with NHL indicated for APSCT for high-risk features at diagnosis partial response to first line treatment and/or relapse were included in the study. There were 66 women and 56 men at median age 45.5 years (range 19-66). 47 patients were with diagnosis of diffuse-large cell lymphoma, 34 with follicular lymphoma, 15 with mantle cell lymphoma and 26 patients had other lymphoma subtypes. Patients were transplanted in years 1997-2004. In all cases BEAM was used for conditioning. Median follow-up of patients was 27.0 months (range 3.0-93.9). 50 (41.0%) patients relapsed and 35 (28.7%) died. Age, stage of disease, IPI, bone marrow and extra-nodal involvement, presence of B sympt

Název v anglickém jazyce

Prognostic Factors for Survival of Patients with Non-Hondgkin´s Lymphoma (NHL) after Autologous Peripheral Stem Cell Transplantation (APSCT) - Signle Center Experience

Popis výsledku anglicky

Several prognostic factors had been previously reported to be associated with overall and progression-free survival of patients with NHL after APSCT. We present a retrospective single center analysis with special attention to the markers that reflect theactivity of disease at the time of transplantation. 122 patients with NHL indicated for APSCT for high-risk features at diagnosis partial response to first line treatment and/or relapse were included in the study. There were 66 women and 56 men at median age 45.5 years (range 19-66). 47 patients were with diagnosis of diffuse-large cell lymphoma, 34 with follicular lymphoma, 15 with mantle cell lymphoma and 26 patients had other lymphoma subtypes. Patients were transplanted in years 1997-2004. In all cases BEAM was used for conditioning. Median follow-up of patients was 27.0 months (range 3.0-93.9). 50 (41.0%) patients relapsed and 35 (28.7%) died. Age, stage of disease, IPI, bone marrow and extra-nodal involvement, presence of B sympt

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biology of Blood and Marrow Transplantation

ISSN

1083-8791

e-ISSN

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Svazek periodika

12

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

181

Strana od-do

120

Kód UT WoS článku

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EID výsledku v databázi Scopus

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