Profesionální expozice azbestu a skelným vláknům a riziko karcinomu plic: multicentrická studie případů a kontrol v Evropě

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F07%3A00004004" target="_blank" >RIV/61989592:15110/07:00004004 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Occupational exposure to asbestos and man-made vitreous fibres and risk of lung cancer: a multicentre case-control study in Europe

Popis výsledku v původním jazyce

Objectives: To investigate the contribution of occupational exposure to asbestos and man-made vitreous fibres (MMVF) to lung cancer in high-risk populations in Europe. Methods: A multi-center case-control study was conducted in six Central and Eastern European countries and the UK, during the period 1998-2002. Comprehensive occupational and socio-demographic information was collected from 2205 newly diagnosed male lung cancer cases and 2305 frequency matched controls. Odds ratios (OR) of lung cancer were calculated after adjusting for other relevant occupational exposures and tobacco smoking. Results: The OR for asbestos exposure was 0.92 (95% confidence interval (CI) 0.73-1.15) in Central and Eastern Europe and 1.85 (95%CI 1.07-3.21) in the UK. Similar OR were found for exposure to amphibole asbestos. The OR for MMVF exposure was 1.23 (95%CI 0.88-1.71) with no evidence of heterogeneity by country. No synergistic effect either between asbestos and MMVF or between any of them and smokin

Název v anglickém jazyce

Occupational exposure to asbestos and man-made vitreous fibres and risk of lung cancer: a multicentre case-control study in Europe

Popis výsledku anglicky

Objectives: To investigate the contribution of occupational exposure to asbestos and man-made vitreous fibres (MMVF) to lung cancer in high-risk populations in Europe. Methods: A multi-center case-control study was conducted in six Central and Eastern European countries and the UK, during the period 1998-2002. Comprehensive occupational and socio-demographic information was collected from 2205 newly diagnosed male lung cancer cases and 2305 frequency matched controls. Odds ratios (OR) of lung cancer were calculated after adjusting for other relevant occupational exposures and tobacco smoking. Results: The OR for asbestos exposure was 0.92 (95% confidence interval (CI) 0.73-1.15) in Central and Eastern Europe and 1.85 (95%CI 1.07-3.21) in the UK. Similar OR were found for exposure to amphibole asbestos. The OR for MMVF exposure was 1.23 (95%CI 0.88-1.71) with no evidence of heterogeneity by country. No synergistic effect either between asbestos and MMVF or between any of them and smokin

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/NR9029" target="_blank" >NR9029: Epidemiologická studie genetických a behaviorálních rizikových faktorů karcinomu pankreatu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Occupational and Environmental Medicine

ISSN

1351-0711

e-ISSN

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Svazek periodika

64

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

502-508

Kód UT WoS článku

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EID výsledku v databázi Scopus

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