Jedna umbilikální arterie ve druhém trimestru těhotenství: spojitost s výskytem chomozomálních aberací

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F07%3A00004203" target="_blank" >RIV/61989592:15110/07:00004203 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Single umbilical artery and its siding in the second trimester of pregnancy: Relation to chromosomal defects.

Popis výsledku v původním jazyce

Objectives To determine the possible association between single umbilical artery (SUA) in the second trimester of pregnancy and the incidence of chromosomal abnormalities. To determine whether the presence of chromosomal defects in fetuses with SUA is related to the side of the missing artery. Methods Color flow imaging of the fetal pelvis was used to determine the number of umbilical arteries in 2147 fetuses immediately before amniocentesis for karyotyping in the second trimester of pregnancy. ResultsSUA was diagnosed in 102/2147 (4.8%) cases. The left umbilical artery was absent in 60/102 (58.8%) fetuses, compared with 42/102 (41,2%) for the right artery. The rate of chromosome abnormalities was significantly higher among fetuses with SUA than amongthose with 2 umbilical arteries (19/102 or 18.6% vs 109/2045 or 5.3%; OR = 4.1, 95% CI 2.3-7.1, p<0.0001). Among fetuses with SUA, there was no significant difference in the rate of chromosome abnormalities between those with absence of

Název v anglickém jazyce

Single umbilical artery and its siding in the second trimester of pregnancy: Relation to chromosomal defects.

Popis výsledku anglicky

Objectives To determine the possible association between single umbilical artery (SUA) in the second trimester of pregnancy and the incidence of chromosomal abnormalities. To determine whether the presence of chromosomal defects in fetuses with SUA is related to the side of the missing artery. Methods Color flow imaging of the fetal pelvis was used to determine the number of umbilical arteries in 2147 fetuses immediately before amniocentesis for karyotyping in the second trimester of pregnancy. ResultsSUA was diagnosed in 102/2147 (4.8%) cases. The left umbilical artery was absent in 60/102 (58.8%) fetuses, compared with 42/102 (41,2%) for the right artery. The rate of chromosome abnormalities was significantly higher among fetuses with SUA than amongthose with 2 umbilical arteries (19/102 or 18.6% vs 109/2045 or 5.3%; OR = 4.1, 95% CI 2.3-7.1, p<0.0001). Among fetuses with SUA, there was no significant difference in the rate of chromosome abnormalities between those with absence of

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Prenatal Diagnosis

ISSN

0197-3851

e-ISSN

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Svazek periodika

27

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

327-331

Kód UT WoS článku

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EID výsledku v databázi Scopus

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