Význam stanovení hladiny leukocytů ve slině pro posouzení stomatitidy a přihojení štěpu u pacientů autologně transplantovaných pro myelom a lymfom.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A00007541" target="_blank" >RIV/61989592:15110/08:00007541 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The salivary neutrophil level as an early indicator of engraftment after autologous transplantation for myeloma and lymphoma. The role of patient education and preventive dentristry for oral mucositis rescue

Popis výsledku v původním jazyce

Objectives: Analysis of neutrophil levels in the saliva as the early marker of stem cells engraftment after autologous transplantation (ASCT) myelomas and lymphomas patients. Evaluation of risk factors for oral mucositis (OM) to improve stomatological care before transplantation. Methods: Results of prospective study (started January 2006) after obtaining ethics commitee approval are reported. 27 patients treated for multiple myeloma (MM), Hodgkin´s (MH) and non-hodgkins lymphoma (NHL) were stomatologically examined before, during and after planned high-dose chemotherapy with ASCT to evaluate OM according to NCI-CTC and WHO classfication.Before the beginning of hematooncological treatment all potential sources of odontogenic infection and/or local irritation of oral mucosa were removed. The conditioning regimen included high-dose melphalan for MM and BEAM regimen for NHL, MH. Supportive care was administered according to standard institutional practise. Neutrophil levels in saliva were

Název v anglickém jazyce

The salivary neutrophil level as an early indicator of engraftment after autologous transplantation for myeloma and lymphoma. The role of patient education and preventive dentristry for oral mucositis rescue

Popis výsledku anglicky

Objectives: Analysis of neutrophil levels in the saliva as the early marker of stem cells engraftment after autologous transplantation (ASCT) myelomas and lymphomas patients. Evaluation of risk factors for oral mucositis (OM) to improve stomatological care before transplantation. Methods: Results of prospective study (started January 2006) after obtaining ethics commitee approval are reported. 27 patients treated for multiple myeloma (MM), Hodgkin´s (MH) and non-hodgkins lymphoma (NHL) were stomatologically examined before, during and after planned high-dose chemotherapy with ASCT to evaluate OM according to NCI-CTC and WHO classfication.Before the beginning of hematooncological treatment all potential sources of odontogenic infection and/or local irritation of oral mucosa were removed. The conditioning regimen included high-dose melphalan for MM and BEAM regimen for NHL, MH. Supportive care was administered according to standard institutional practise. Neutrophil levels in saliva were

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bone Marrow Transplantation

ISSN

0268-3369

e-ISSN

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Svazek periodika

41

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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