Multiple myeloma: scintigraphy using technetium-99m-2-methoxyisobutylisonitrile

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Multiple myeloma: scintigraphy using technetium-99m-2-methoxyisobutylisonitrile

Popis výsledku v původním jazyce

Multiple myeloma (MM) is a clonal B-lymphocyte neoplasm of plasma cells. It accounts for 1% of all malignant diseases and represents 10% of hematologic malignancies. The hallmark of MM is the presence of a monoclonal protein (MIG), produced by the abnormal plasma cells in the blood or urine. The whole body scintigraphy using Tc-99m-MIBI seems to be an easy, sensitive, and available parameter of biological activity of multiple myeloma (MM). Individual patterns of Tc-99m-MIBI uptake in MM patients showeda close association with the grade of disease activity, correlation with clinical stage of the disease and allowed with high sensitivity the discrimination of the patients in remission from those with recurrent disease. Patients with MGUS had mostly physiological pattern of Tc-99m-MIBI uptake, or only a very low activity of diffuse pattern.

Název v anglickém jazyce

Multiple myeloma: scintigraphy using technetium-99m-2-methoxyisobutylisonitrile

Popis výsledku anglicky

Multiple myeloma (MM) is a clonal B-lymphocyte neoplasm of plasma cells. It accounts for 1% of all malignant diseases and represents 10% of hematologic malignancies. The hallmark of MM is the presence of a monoclonal protein (MIG), produced by the abnormal plasma cells in the blood or urine. The whole body scintigraphy using Tc-99m-MIBI seems to be an easy, sensitive, and available parameter of biological activity of multiple myeloma (MM). Individual patterns of Tc-99m-MIBI uptake in MM patients showeda close association with the grade of disease activity, correlation with clinical stage of the disease and allowed with high sensitivity the discrimination of the patients in remission from those with recurrent disease. Patients with MGUS had mostly physiological pattern of Tc-99m-MIBI uptake, or only a very low activity of diffuse pattern.

Druh

C - Kapitola v odborné knize

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Cancer imaging, Instrumentation and applications

ISBN

978-0-12-374183-7

Počet stran výsledku

6

Strana od-do

499-504

Počet stran knihy

733

Název nakladatele

Elsevier Ltd.

Místo vydání

London

Kód UT WoS kapitoly

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