Prediction of long-term reverse left ventricular remodeling after revascularization or medical treatment in patients with ischemic cardiomyopathy: a comparative study between SPECT and MRI.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F10%3A10216290" target="_blank" >RIV/61989592:15110/10:10216290 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Prediction of long-term reverse left ventricular remodeling after revascularization or medical treatment in patients with ischemic cardiomyopathy: a comparative study between SPECT and MRI.

Popis výsledku v původním jazyce

Patients with ischemic heart disease (IHD) develop varying degrees of LV remodeling after cardiac surgical revascularization. 53 patients with IHD and impaired LV function (EF 34.9 +- 4%) were prospectively followed up for 24 months. 37 patients underwent coronary artery bypass grafting (CABG), 16 patients were treated conservatively. Cardiac magnetic resonance (MR) and SPECT were performed at baseline and after 12 and 24 months of follow-up. Patients were divided into responders and non-responders depending on the degree of LVEF improvement at 24 months follow-up (}5%=responders). MRI with ?5 segments with DE/wall thickness ratio (DEWTR) ?50% predicted LV reverse remodeling with sensitivity of 86% and specificity of 75%. MRI finding of ?2 segments with the DEWTR ?75% had sensitivity of 71% and specificity of 67%, while fixed perfusion defect on SPECT { 16.5% of LV had sensitivity of 64% and specificity of 69%. No other MRI or SPECT parameter predicted LVEF improvement at 24 months aft

Název v anglickém jazyce

Prediction of long-term reverse left ventricular remodeling after revascularization or medical treatment in patients with ischemic cardiomyopathy: a comparative study between SPECT and MRI.

Popis výsledku anglicky

Patients with ischemic heart disease (IHD) develop varying degrees of LV remodeling after cardiac surgical revascularization. 53 patients with IHD and impaired LV function (EF 34.9 +- 4%) were prospectively followed up for 24 months. 37 patients underwent coronary artery bypass grafting (CABG), 16 patients were treated conservatively. Cardiac magnetic resonance (MR) and SPECT were performed at baseline and after 12 and 24 months of follow-up. Patients were divided into responders and non-responders depending on the degree of LVEF improvement at 24 months follow-up (}5%=responders). MRI with ?5 segments with DE/wall thickness ratio (DEWTR) ?50% predicted LV reverse remodeling with sensitivity of 86% and specificity of 75%. MRI finding of ?2 segments with the DEWTR ?75% had sensitivity of 71% and specificity of 67%, while fixed perfusion defect on SPECT { 16.5% of LV had sensitivity of 64% and specificity of 69%. No other MRI or SPECT parameter predicted LVEF improvement at 24 months aft

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The International Journal of Cardiovascular Imaging

ISSN

1569-5794

e-ISSN

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Svazek periodika

27

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

343-353

Kód UT WoS článku

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EID výsledku v databázi Scopus

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