Influence of age and gender on the pharmacodynamic parameters of rocuronium during total intravenous anesthesia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F11%3A33115963" target="_blank" >RIV/61989592:15110/11:33115963 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/11:#0000109

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Influence of age and gender on the pharmacodynamic parameters of rocuronium during total intravenous anesthesia

Popis výsledku v původním jazyce

Aims. To compare the pharmacodynamics of 0.6 mg kg-1 rocuronium in young and older patients of both genders during total intravenous anesthesia. Methods. Following local ethics committee approval and informed consent, patients scheduled for surgery undertotal intravenous anesthesia (propofol/sufentanil) were divided into 4 study groups: 37 males aged 20-40, 40 males aged 60-75 yrs, 43 females aged 20-40 and 38 females aged 60-75 yrs. Neuromuscular block following rocuronium (0.6 mg kg-1) was monitored:train-of-four [TOF] stimulation of the ulnar nerve at 15-s intervals, EMG of the adductor pollicis muscle. The onset time (from application of rocuronium to maximum depression of T1), clinical duration (from application to 25% recovery of T1), and timeto full spontaneous recovery (from application to TOF-ratio ? 0.9) were determined for each patient.

Název v anglickém jazyce

Influence of age and gender on the pharmacodynamic parameters of rocuronium during total intravenous anesthesia

Popis výsledku anglicky

Aims. To compare the pharmacodynamics of 0.6 mg kg-1 rocuronium in young and older patients of both genders during total intravenous anesthesia. Methods. Following local ethics committee approval and informed consent, patients scheduled for surgery undertotal intravenous anesthesia (propofol/sufentanil) were divided into 4 study groups: 37 males aged 20-40, 40 males aged 60-75 yrs, 43 females aged 20-40 and 38 females aged 60-75 yrs. Neuromuscular block following rocuronium (0.6 mg kg-1) was monitored:train-of-four [TOF] stimulation of the ulnar nerve at 15-s intervals, EMG of the adductor pollicis muscle. The onset time (from application of rocuronium to maximum depression of T1), clinical duration (from application to 25% recovery of T1), and timeto full spontaneous recovery (from application to TOF-ratio ? 0.9) were determined for each patient.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

<a href="/cs/project/NS9618" target="_blank" >NS9618: Epidemiologická studie predikce obtížné tracheální intubace v anesteziologii</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers-Olomouc

ISSN

1213-8118

e-ISSN

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Svazek periodika

155

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

233-240

Kód UT WoS článku

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EID výsledku v databázi Scopus

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