The response of osteoblast-like SaOS-2 cells to modified titanium surfaces.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33144554" target="_blank" >RIV/61989592:15110/13:33144554 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.quintpub.com/journals/omi/abstract.php?article_id=13597" target="_blank" >http://www.quintpub.com/journals/omi/abstract.php?article_id=13597</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.11607/jomi.3039" target="_blank" >10.11607/jomi.3039</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The response of osteoblast-like SaOS-2 cells to modified titanium surfaces.

Popis výsledku v původním jazyce

Purpose: To study the effects of different chemically modified titanium surfaces on the proliferation, differentiation, adhesion and apoptosis of osteoblast-like SaOS-2 cells. Materials and Methods: In this work, six different titanium materials: i) glazed, ii) unglazed, iii) unglazed and alkali etched, iv) unglazed sand blasted acid and alkali etched, v) unglazed and coated with ZrN, vi) unglazed sand blasted and acid etched, were compared with cells on plastic. The production of alkaline phosphatase (ALP), tumor necrosis factor alpha (TNF-a), matrix metalloproteinase-2 (MMP-2) and the expression of adhesion proteins (integrin a3b1, vinculin) were evaluated using ELISA methods. Finally, the apoptosis of cells was analyzed by flow cytometry. Results: The most significant differences were found for unglazed sand blasted acid and alkali etched titanium disc in comparison with cells on plastic. The proliferation was decreased after 96 h. The production of TNF-a was decreased after 24 h as

Název v anglickém jazyce

The response of osteoblast-like SaOS-2 cells to modified titanium surfaces.

Popis výsledku anglicky

Purpose: To study the effects of different chemically modified titanium surfaces on the proliferation, differentiation, adhesion and apoptosis of osteoblast-like SaOS-2 cells. Materials and Methods: In this work, six different titanium materials: i) glazed, ii) unglazed, iii) unglazed and alkali etched, iv) unglazed sand blasted acid and alkali etched, v) unglazed and coated with ZrN, vi) unglazed sand blasted and acid etched, were compared with cells on plastic. The production of alkaline phosphatase (ALP), tumor necrosis factor alpha (TNF-a), matrix metalloproteinase-2 (MMP-2) and the expression of adhesion proteins (integrin a3b1, vinculin) were evaluated using ELISA methods. Finally, the apoptosis of cells was analyzed by flow cytometry. Results: The most significant differences were found for unglazed sand blasted acid and alkali etched titanium disc in comparison with cells on plastic. The proliferation was decreased after 96 h. The production of TNF-a was decreased after 24 h as

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Oral Maxillofacial Implants

ISSN

0882-2786

e-ISSN

—

Svazek periodika

28

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

1386-1394

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—