Extrapulmonary involvement in patients with sarcoidosis and comparison of routine laboratory and clinical data to pulmonary involvement

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33151345" target="_blank" >RIV/61989592:15110/14:33151345 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/14:#0000776

Výsledek na webu

<a href="http://dx.doi.org/10.5507/bp.2014.026" target="_blank" >http://dx.doi.org/10.5507/bp.2014.026</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2014.026" target="_blank" >10.5507/bp.2014.026</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Extrapulmonary involvement in patients with sarcoidosis and comparison of routine laboratory and clinical data to pulmonary involvement

Popis výsledku v původním jazyce

Introduction. Patients with pulmonary and pulmonary plus extrapulmonary sarcoidosis differ in symptom severity and health status impairment. To date there is no information on differences in clinical and laboratory parameters between these phenotypes andlimited information on extrapulmonary involvement in Czech sarcoidosis patients exists. Methods. We therefore compared clinical data (age, gender, organ involvement, lung function tests) and laboratory data (blood counts, bronchoalveolar fluid (BAL) cellular profile, serum levels of CRP, SACE, sIL-2R, neopterin) between patients with newly diagnosed pulmonary sarcoidosis (n=107) and those with pulmonary plus extrapulmonary sarcoidosis (n=54). Results. Extrapulmonary sarcoidosis was diagnosed in 33 % ofpatients, mostly affecting lymph nodes and skin and having hypercalciuria. There was no difference in the prevalence of extrapulmonary sarcoidosis between genders. Patients with extrapulmonary sarcoidosis were older and mostly non-smoker

Název v anglickém jazyce

Extrapulmonary involvement in patients with sarcoidosis and comparison of routine laboratory and clinical data to pulmonary involvement

Popis výsledku anglicky

Introduction. Patients with pulmonary and pulmonary plus extrapulmonary sarcoidosis differ in symptom severity and health status impairment. To date there is no information on differences in clinical and laboratory parameters between these phenotypes andlimited information on extrapulmonary involvement in Czech sarcoidosis patients exists. Methods. We therefore compared clinical data (age, gender, organ involvement, lung function tests) and laboratory data (blood counts, bronchoalveolar fluid (BAL) cellular profile, serum levels of CRP, SACE, sIL-2R, neopterin) between patients with newly diagnosed pulmonary sarcoidosis (n=107) and those with pulmonary plus extrapulmonary sarcoidosis (n=54). Results. Extrapulmonary sarcoidosis was diagnosed in 33 % ofpatients, mostly affecting lymph nodes and skin and having hypercalciuria. There was no difference in the prevalence of extrapulmonary sarcoidosis between genders. Patients with extrapulmonary sarcoidosis were older and mostly non-smoker

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FC - Pneumologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT11117" target="_blank" >NT11117: Studium mediátorů fibrotizačních procesů u pacientů s difuzními plicními nemocemi a jejich aplikace v diagnostice</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers-Olomouc

ISSN

1213-8118

e-ISSN

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Svazek periodika

158

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

613-620

Kód UT WoS článku

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EID výsledku v databázi Scopus

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