Intima media thickness measurement as a marker of subclinical atherosclerosis in SLE patient

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33152002" target="_blank" >RIV/61989592:15110/14:33152002 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/14:#0000801

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Intima media thickness measurement as a marker of subclinical atherosclerosis in SLE patient

Popis výsledku v původním jazyce

Accelerated atherosclerosis in sytemic lupus erythematosus (SLE) is an important cause of morbidity and mortality. The pathophysiology of accelerated atherosclerosis in SLE is mediated by factors such as inflammatory processes in the vascular wall, specific antibodies, dylipoproteinemia, endothelial dysfunction and the high prevalence of traditional risk factors for cardiovascular disease. In this kontext, we evluated the clinical signifikance of ultrasound examination of the Hrotic arteries in the early diagnosis of atherosclerosis. The study included 63 patients with SLE (female: male 53:10, 38.4?12.7 years, mean disease durativ 143,0?82,6 months), 24 patients had lupus nephritis. The control group consisted of 24 volunteers (female: male 20:4 mean age 31,04?8.59). Intima media thickness (IMT) was measured by ultrasound on both sides. The results were correlated with markers of lipid spektrum, anti-dsDNA, antinucleosomal and anticardiolipin antibodies, lupus antikoagulant and komplem

Název v anglickém jazyce

Intima media thickness measurement as a marker of subclinical atherosclerosis in SLE patient

Popis výsledku anglicky

Accelerated atherosclerosis in sytemic lupus erythematosus (SLE) is an important cause of morbidity and mortality. The pathophysiology of accelerated atherosclerosis in SLE is mediated by factors such as inflammatory processes in the vascular wall, specific antibodies, dylipoproteinemia, endothelial dysfunction and the high prevalence of traditional risk factors for cardiovascular disease. In this kontext, we evluated the clinical signifikance of ultrasound examination of the Hrotic arteries in the early diagnosis of atherosclerosis. The study included 63 patients with SLE (female: male 53:10, 38.4?12.7 years, mean disease durativ 143,0?82,6 months), 24 patients had lupus nephritis. The control group consisted of 24 volunteers (female: male 20:4 mean age 31,04?8.59). Intima media thickness (IMT) was measured by ultrasound on both sides. The results were correlated with markers of lipid spektrum, anti-dsDNA, antinucleosomal and anticardiolipin antibodies, lupus antikoagulant and komplem

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers-Olomouc

ISSN

1213-8118

e-ISSN

—

Svazek periodika

158

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

404-411

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—