Hypertriglyceridemic waist - a simple clinical tool to detect cardiometabolic risk: comparison with harmonized definition of metabolic syndrome

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33156462" target="_blank" >RIV/61989592:15110/15:33156462 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/15:#0000875

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Hypertriglyceridemic waist - a simple clinical tool to detect cardiometabolic risk: comparison with harmonized definition of metabolic syndrome

Popis výsledku v původním jazyce

With the increasing prevalence of obesity and especially abdominal obesity, a simple clinical tool is needed that identifies the cardiometabolic risk for cardiovascular disease and type 2 diabetes. The aim of our study was to evaluate a broad spectrum ofmetabolic variables and IMT in subjects with and without hypertriglyceridemic waist (HTGW) and compare it with the harmonized definition of metabolic syndrome (MS) with both a higher (MS-I) and lower waist circumference (MS-II) for Europids. We enrolled607 asymptomatic dyslipidemic subjects (295 men and 312 wmen) into our cross-sectional study. The subjects with HTGW had an atherogenic lipid profile (significantly higher triglycerides, A/P, non-HDL-C, lower HDL-C and ApoA-1 and the women also higher TC and ApoB), increased markers of insulin resistence (insulin, HOMA, C-peptide, proinsulin), inflammation (hsCRP), thrombosis (fibrinogen, PAI-1), SBP and DBP, and lower adiponectin. These risk factors were entirely similar in HTGW, MS-I

Název v anglickém jazyce

Hypertriglyceridemic waist - a simple clinical tool to detect cardiometabolic risk: comparison with harmonized definition of metabolic syndrome

Popis výsledku anglicky

With the increasing prevalence of obesity and especially abdominal obesity, a simple clinical tool is needed that identifies the cardiometabolic risk for cardiovascular disease and type 2 diabetes. The aim of our study was to evaluate a broad spectrum ofmetabolic variables and IMT in subjects with and without hypertriglyceridemic waist (HTGW) and compare it with the harmonized definition of metabolic syndrome (MS) with both a higher (MS-I) and lower waist circumference (MS-II) for Europids. We enrolled607 asymptomatic dyslipidemic subjects (295 men and 312 wmen) into our cross-sectional study. The subjects with HTGW had an atherogenic lipid profile (significantly higher triglycerides, A/P, non-HDL-C, lower HDL-C and ApoA-1 and the women also higher TC and ApoB), increased markers of insulin resistence (insulin, HOMA, C-peptide, proinsulin), inflammation (hsCRP), thrombosis (fibrinogen, PAI-1), SBP and DBP, and lower adiponectin. These risk factors were entirely similar in HTGW, MS-I

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological Research (print)

ISSN

0862-8408

e-ISSN

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Svazek periodika

64

Číslo periodika v rámci svazku

suppl. 3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

10

Strana od-do

"S385"-"S394"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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