DatSCAN In Differential Diagnostics of Lewy Body Disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F16%3A33160800" target="_blank" >RIV/61989592:15110/16:33160800 - isvavai.cz</a>

Výsledek na webu

<a href="http://eds.a.ebscohost.com/eds/pdfviewer/pdfviewer?sid=ae5a4c1e-2ad7-49b3-8a44-8c98feca532c%40sessionmgr4006&vid=1&hid=4203" target="_blank" >http://eds.a.ebscohost.com/eds/pdfviewer/pdfviewer?sid=ae5a4c1e-2ad7-49b3-8a44-8c98feca532c%40sessionmgr4006&vid=1&hid=4203</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

DatSCAN In Differential Diagnostics of Lewy Body Disease

Popis výsledku v původním jazyce

Differential diagnosis between Lewy body disease and Alzheimer's disease might be difficult because of similarities of clinical symptoms in both neurodegenerative diseases. DatSCAN is a modern functional neuroimmaging method which differentiates between this similar diseases and helps in correct treatment strategy. We report our positive experience with DatSCAN in differentiating Lewy body disease from Alzheimer's disease. This is a case report of a woman with Lewy body disease, initially diagnosed as Alzheimer's disease. DatSCAN neuroimmaging method was used in differential diagnosis of dementia. Memory impairment, impaired activities of daily living, sleep and behavioral disturbances were present in our case. Donepezil was well tolerated, but haloperidol administration was followed by development of severe dystonia. DatSCAN showed deficient dopaminergic presynaptic transport in substantia nigra and striatum. This finding is typical for Lewy body disease not for Alzheimer's disease. DatSCAN neuroimmaging is a suitable method for differentiating Lewy body disease from Alzheimer's disease. Deficient dopaminergic presynaptic transport in substantia nigra and striatum is typical for Lewy body disease.

Název v anglickém jazyce

DatSCAN In Differential Diagnostics of Lewy Body Disease

Popis výsledku anglicky

Differential diagnosis between Lewy body disease and Alzheimer's disease might be difficult because of similarities of clinical symptoms in both neurodegenerative diseases. DatSCAN is a modern functional neuroimmaging method which differentiates between this similar diseases and helps in correct treatment strategy. We report our positive experience with DatSCAN in differentiating Lewy body disease from Alzheimer's disease. This is a case report of a woman with Lewy body disease, initially diagnosed as Alzheimer's disease. DatSCAN neuroimmaging method was used in differential diagnosis of dementia. Memory impairment, impaired activities of daily living, sleep and behavioral disturbances were present in our case. Donepezil was well tolerated, but haloperidol administration was followed by development of severe dystonia. DatSCAN showed deficient dopaminergic presynaptic transport in substantia nigra and striatum. This finding is typical for Lewy body disease not for Alzheimer's disease. DatSCAN neuroimmaging is a suitable method for differentiating Lewy body disease from Alzheimer's disease. Deficient dopaminergic presynaptic transport in substantia nigra and striatum is typical for Lewy body disease.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FQ - Veřejné zdravotnictví, sociální lékařství

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Archives of Iranian Medicine

ISSN

1029-2977

e-ISSN

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Svazek periodika

19

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

IR - Íránská islámská republika

Počet stran výsledku

4

Strana od-do

449-452

Kód UT WoS článku

000378109300012

EID výsledku v databázi Scopus

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