Optimal reconstruction matrix and PET image filtration for point-spread function and time-of-flight reconstruction – A phantom study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73583072" target="_blank" >RIV/61989592:15110/17:73583072 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/17:N0000065

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ejmp.2017.06.002" target="_blank" >http://dx.doi.org/10.1016/j.ejmp.2017.06.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejmp.2017.06.002" target="_blank" >10.1016/j.ejmp.2017.06.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Optimal reconstruction matrix and PET image filtration for point-spread function and time-of-flight reconstruction – A phantom study

Popis výsledku v původním jazyce

Introduction: The aim of this study was to determine the optimal image matrix and half-width of the Gaussian filter after iterative reconstruction of the PET image with point-spread function (PSF) and time-of-flight (TOF) correction, based on measuring the recovery coefficient (RC) curves. The measured RC curves were compared to those from an older system which does not use PSF and TOF corrections. Materials and methods: The measurements were carried out on a NEMA IEC Body Phantom. We measured the RC curves based on SUVmax and SUVA50 in source spheres with different diameters. The change in noise level for different reconstruction parameter settings and the relation between RC curves and the administered activity were also evaluated. Results: With an increasing size of image matrix and reduction in the half-width of the postreconstruction Gaussian filter, there was a significant increase in image noise and overestimation of the SUV. The local increase in SUV, observed for certain filtrations and objects with a diameter below 13 mm, was caused by PSF correction. The decrease in administered activity, while maintaining the same conditions of acquisition and reconstruction, also led to overestimation of readings of the SUV and additionally to deterioration in reproducibility. Conclusion: This study proposes a suitable size for the image matrix and filtering for displaying PET and SUV measurements. The benefits were demonstrated as improved image parameters for the newer instrument, these even being found using relatively strong filtration of the reconstructed images.

Název v anglickém jazyce

Optimal reconstruction matrix and PET image filtration for point-spread function and time-of-flight reconstruction – A phantom study

Popis výsledku anglicky

Introduction: The aim of this study was to determine the optimal image matrix and half-width of the Gaussian filter after iterative reconstruction of the PET image with point-spread function (PSF) and time-of-flight (TOF) correction, based on measuring the recovery coefficient (RC) curves. The measured RC curves were compared to those from an older system which does not use PSF and TOF corrections. Materials and methods: The measurements were carried out on a NEMA IEC Body Phantom. We measured the RC curves based on SUVmax and SUVA50 in source spheres with different diameters. The change in noise level for different reconstruction parameter settings and the relation between RC curves and the administered activity were also evaluated. Results: With an increasing size of image matrix and reduction in the half-width of the postreconstruction Gaussian filter, there was a significant increase in image noise and overestimation of the SUV. The local increase in SUV, observed for certain filtrations and objects with a diameter below 13 mm, was caused by PSF correction. The decrease in administered activity, while maintaining the same conditions of acquisition and reconstruction, also led to overestimation of readings of the SUV and additionally to deterioration in reproducibility. Conclusion: This study proposes a suitable size for the image matrix and filtering for displaying PET and SUV measurements. The benefits were demonstrated as improved image parameters for the newer instrument, these even being found using relatively strong filtration of the reconstructed images.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10304 - Nuclear physics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physica Medica

ISSN

1120-1797

e-ISSN

—

Svazek periodika

39

Číslo periodika v rámci svazku

2017 JUL

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

95-99

Kód UT WoS článku

000405493200013

EID výsledku v databázi Scopus

2-s2.0-85020408254