Antifungal susceptibility patterns of opportunistic pathogens from the Aspergillus viridinutans complex (section Fumigati) determined by the EUCAST E.DEF 9.3 method and Sensititre YeastOne colorimetric antifungal panel

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73587435" target="_blank" >RIV/61989592:15110/17:73587435 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Antifungal susceptibility patterns of opportunistic pathogens from the Aspergillus viridinutans complex (section Fumigati) determined by the EUCAST E.DEF 9.3 method and Sensititre YeastOne colorimetric antifungal panel

Popis výsledku v původním jazyce

Invasive aspergillosis (IA) is one of the major fungal infections, causing high fatality rates among severely immunocompromised patients. Although the main etiologic agent of IA is Aspergillus fumigatus, other Aspergillus species belonging to section Fumigati (so-called cryptic species) may occasionally cause IA. These species are morphologically similar to each other and are often misidentified by conventional identification techniques. These A. fumigatus-related species often display some level of intrinsic resistance to azoles and other antifungal drugs. The A. viridinutans species complex (AVSC) contains morphologically similar, soil-inhabiting species that have increasingly been reported as opportunistic human and animal pathogens in recent years. Compared to A. fumigatus, AVSC species proved to be resistant to a wider variety of antifungal agents. Material and Methods: The aim of this study was to evaluate in vitro antifungal susceptibility patterns of 90 strains from the AVSC (27 A. felis, 17 A. udagawae, 15 A. wyomingensis, 13 A. arcoverdensis, 7 A. pseudoviridinutans, 5 Aspergillus spp., three A. aureolus, two A. siamensis, and one A. viridinutans) to seven antifungals (voriconazole, itraconazole, posaconazole, amphotericin B, anidulafungin, micafungin and caspofungin).

Název v anglickém jazyce

Antifungal susceptibility patterns of opportunistic pathogens from the Aspergillus viridinutans complex (section Fumigati) determined by the EUCAST E.DEF 9.3 method and Sensititre YeastOne colorimetric antifungal panel

Popis výsledku anglicky

Invasive aspergillosis (IA) is one of the major fungal infections, causing high fatality rates among severely immunocompromised patients. Although the main etiologic agent of IA is Aspergillus fumigatus, other Aspergillus species belonging to section Fumigati (so-called cryptic species) may occasionally cause IA. These species are morphologically similar to each other and are often misidentified by conventional identification techniques. These A. fumigatus-related species often display some level of intrinsic resistance to azoles and other antifungal drugs. The A. viridinutans species complex (AVSC) contains morphologically similar, soil-inhabiting species that have increasingly been reported as opportunistic human and animal pathogens in recent years. Compared to A. fumigatus, AVSC species proved to be resistant to a wider variety of antifungal agents. Material and Methods: The aim of this study was to evaluate in vitro antifungal susceptibility patterns of 90 strains from the AVSC (27 A. felis, 17 A. udagawae, 15 A. wyomingensis, 13 A. arcoverdensis, 7 A. pseudoviridinutans, 5 Aspergillus spp., three A. aureolus, two A. siamensis, and one A. viridinutans) to seven antifungals (voriconazole, itraconazole, posaconazole, amphotericin B, anidulafungin, micafungin and caspofungin).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10612 - Mycology

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mycoses

ISSN

0933-7407

e-ISSN

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Svazek periodika

60

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

1

Strana od-do

71

Kód UT WoS článku

000411715800120

EID výsledku v databázi Scopus

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