The differences between patients with panic disorder and healthy controls in psychophysiological stress profile
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F18%3A73589424" target="_blank" >RIV/61989592:15110/18:73589424 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.2147/NDT.S153005" target="_blank" >http://dx.doi.org/10.2147/NDT.S153005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/NDT.S153005" target="_blank" >10.2147/NDT.S153005</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The differences between patients with panic disorder and healthy controls in psychophysiological stress profile
Popis výsledku v původním jazyce
Background: Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the detection of autonomic instabilities in various clinical disorders. Our study aimed to compare patients with panic disorder and healthy controls in heart rate variation (HRV) parameters (very-low-frequency [VLF], low-frequency [LF], and high-frequency [HF] band components of R-R interval) in baseline and during the response to the mental task. Subjects and methods: We assessed psychophysiological variables in 33 patients with panic disorder (10 men, 23 women; mean age 35.9 +/- 10.7 years) and 33 age-and gender-matched healthy controls (10 men, 23 women; mean age 35.8 +/- 12.1 years). Patients were treatment naive. Heart rate, blood pressure, muscle tension, and HRV in basal conditions and after the psychological task were assessed. Power spectrum was computed for VLF (0.003-0.04 Hz), LF (0.04-0.15 Hz), and HF (0.15-0.40 Hz) bands using fast Fourier transformation. Results: In the baseline period, the VLF band was significantly lower in panic disorder group compared to controls (p<0.005). In the period of mental task, the LF/HF ratio was significantly higher in panic disorder patients compared to controls (p<0.05). No significant differences were found in the remaining parameters. There was a significant difference in Delta HF and Delta LF/HF ratio between patients and controls, with Delta increasing in patients and decreasing in controls. Conclusion: These findings revealed that patients suffering from panic disorder were characterized by relative sympathetic dominance (reactivity) in response to mental stress compared with healthy controls.
Název v anglickém jazyce
The differences between patients with panic disorder and healthy controls in psychophysiological stress profile
Popis výsledku anglicky
Background: Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the detection of autonomic instabilities in various clinical disorders. Our study aimed to compare patients with panic disorder and healthy controls in heart rate variation (HRV) parameters (very-low-frequency [VLF], low-frequency [LF], and high-frequency [HF] band components of R-R interval) in baseline and during the response to the mental task. Subjects and methods: We assessed psychophysiological variables in 33 patients with panic disorder (10 men, 23 women; mean age 35.9 +/- 10.7 years) and 33 age-and gender-matched healthy controls (10 men, 23 women; mean age 35.8 +/- 12.1 years). Patients were treatment naive. Heart rate, blood pressure, muscle tension, and HRV in basal conditions and after the psychological task were assessed. Power spectrum was computed for VLF (0.003-0.04 Hz), LF (0.04-0.15 Hz), and HF (0.15-0.40 Hz) bands using fast Fourier transformation. Results: In the baseline period, the VLF band was significantly lower in panic disorder group compared to controls (p<0.005). In the period of mental task, the LF/HF ratio was significantly higher in panic disorder patients compared to controls (p<0.05). No significant differences were found in the remaining parameters. There was a significant difference in Delta HF and Delta LF/HF ratio between patients and controls, with Delta increasing in patients and decreasing in controls. Conclusion: These findings revealed that patients suffering from panic disorder were characterized by relative sympathetic dominance (reactivity) in response to mental stress compared with healthy controls.
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
30215 - Psychiatry
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Neuropsychiatric Disease and Treatment
ISSN
1176-6328
e-ISSN
—
Svazek periodika
14
Číslo periodika v rámci svazku
7-Feb-2018
Stát vydavatele periodika
NZ - Nový Zéland
Počet stran výsledku
7
Strana od-do
435-441
Kód UT WoS článku
000425314400001
EID výsledku v databázi Scopus
2-s2.0-85041547852