Causes of death in sleep apnoea petients treated with positive airway pressure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73598850" target="_blank" >RIV/61989592:15110/19:73598850 - isvavai.cz</a>

Výsledek na webu

<a href="https://obd.upol.cz/id_publ/333178736" target="_blank" >https://obd.upol.cz/id_publ/333178736</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Causes of death in sleep apnoea petients treated with positive airway pressure

Popis výsledku v původním jazyce

Backround: According to numerous studies, there is shorter life expectancy and higher all-cause mortality in obstructive sleep apnoea (OSA) patients. The death causes in patients with OSA are not profoundly known. Methods: The study period was January 2002 to June 2017; the subjects were patients of the Sleep Laboratory of the Department of Respiratory Medicine in Olomouc, Czech Republic. The inclusion criteria were OSA and positive airway pressure therapy; the exclusion criteria were the presence of a motor neuron disease and contraindication to airway pressure therapy. The information about causes of death was acquired from medical documentation. Results: Over the analyzed interval, 71 patients treated with positive airway pressure died. Eleven patients were excluded (six patients due to a motor neuron disease, five due to global respiratory insufficiency); the remaining 60 subjects were included in the analysis. The mean length of life was 65.6 years; the mean duration of therapy was 3.29 years; the mean BMI was 36.10 and the mean apnoea-hypopnoea index was 49.02. The most common death cause was pulmonary disease (32.8 %), followed by malignancies (26.2 %), cardiac failure with or without myocardial infarction (21.3 %); in three patients, the cause could not be identified. The most common comorbidity was arterial hypertension (73.3 %). Conclusion: Our patients treated with positive airway pressure died almost 10 years earlier than the general population in the Czech Republic. OSA is a serious disorder with comorbidities leading to premature death.

Název v anglickém jazyce

Causes of death in sleep apnoea petients treated with positive airway pressure

Popis výsledku anglicky

Backround: According to numerous studies, there is shorter life expectancy and higher all-cause mortality in obstructive sleep apnoea (OSA) patients. The death causes in patients with OSA are not profoundly known. Methods: The study period was January 2002 to June 2017; the subjects were patients of the Sleep Laboratory of the Department of Respiratory Medicine in Olomouc, Czech Republic. The inclusion criteria were OSA and positive airway pressure therapy; the exclusion criteria were the presence of a motor neuron disease and contraindication to airway pressure therapy. The information about causes of death was acquired from medical documentation. Results: Over the analyzed interval, 71 patients treated with positive airway pressure died. Eleven patients were excluded (six patients due to a motor neuron disease, five due to global respiratory insufficiency); the remaining 60 subjects were included in the analysis. The mean length of life was 65.6 years; the mean duration of therapy was 3.29 years; the mean BMI was 36.10 and the mean apnoea-hypopnoea index was 49.02. The most common death cause was pulmonary disease (32.8 %), followed by malignancies (26.2 %), cardiac failure with or without myocardial infarction (21.3 %); in three patients, the cause could not be identified. The most common comorbidity was arterial hypertension (73.3 %). Conclusion: Our patients treated with positive airway pressure died almost 10 years earlier than the general population in the Czech Republic. OSA is a serious disorder with comorbidities leading to premature death.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

30203 - Respiratory systems

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Studia Pneumologica et Phthiseologica

ISSN

1213-810X

e-ISSN

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Svazek periodika

79

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

208-213

Kód UT WoS článku

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EID výsledku v databázi Scopus

999