Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73598854" target="_blank" >RIV/61989592:15110/19:73598854 - isvavai.cz</a>
Výsledek na webu
<a href="https://link.springer.com/content/pdf/10.1007/s00044-019-02435-0.pdf" target="_blank" >https://link.springer.com/content/pdf/10.1007/s00044-019-02435-0.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00044-019-02435-0" target="_blank" >10.1007/s00044-019-02435-0</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action
Popis výsledku v původním jazyce
Malaria is a multifaceted tropical disease that has been transmitted by the bite of female Anopheles mosquitoes (Plewes et al. 2019). Five species are responsible for the infection Plasmodium falciparum, vivax, ovale, malariae, and lastly Knowlesi (Plewes et al. 2019). According to the World Malaria Report (World Health Organization 2018), there is an increase in malaria cases, more than 2 million from 2016 (217 million cases) to 2017 (219 million cases), the estimated number of malaria deaths stood at 435,000 in 2017. The increase is due to the lack of proper controls in several countries (Grillet et al. 2019). It is concluded that new approaches for treatment are urgently needed. Malaria incidence can be decreased through vector control; however, resistance to insecticides and chemotherapeutics have difficulted the task (WHO 2018; Grillet et al. 2019).
Název v anglickém jazyce
Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action
Popis výsledku anglicky
Malaria is a multifaceted tropical disease that has been transmitted by the bite of female Anopheles mosquitoes (Plewes et al. 2019). Five species are responsible for the infection Plasmodium falciparum, vivax, ovale, malariae, and lastly Knowlesi (Plewes et al. 2019). According to the World Malaria Report (World Health Organization 2018), there is an increase in malaria cases, more than 2 million from 2016 (217 million cases) to 2017 (219 million cases), the estimated number of malaria deaths stood at 435,000 in 2017. The increase is due to the lack of proper controls in several countries (Grillet et al. 2019). It is concluded that new approaches for treatment are urgently needed. Malaria incidence can be decreased through vector control; however, resistance to insecticides and chemotherapeutics have difficulted the task (WHO 2018; Grillet et al. 2019).
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
10608 - Biochemistry and molecular biology
Návaznosti výsledku
Projekt
—
Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
MEDICINAL CHEMISTRY RESEARCH
ISSN
1054-2523
e-ISSN
—
Svazek periodika
2019
Číslo periodika v rámci svazku
28
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
17
Strana od-do
2050-2066
Kód UT WoS článku
000489305700020
EID výsledku v databázi Scopus
2-s2.0-85074209326