Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73598857" target="_blank" >RIV/61989592:15110/19:73598857 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0039128X18302113?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0039128X18302113?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.steroids.2018.11.007" target="_blank" >10.1016/j.steroids.2018.11.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

Popis výsledku v původním jazyce

In recent years, the interest in metabolic-type and natural products drugs that have the ability to activate plastic processes in various organs and tissues, improve the energy status of their cellular systems, and thereby improve the body resistance to various adverse factors, increased significantly. According to the results of the experimental and clinical studies, one of the most effective drugs in this area could be “Ecdisten” (Five Stars Laboratory, Bulgaria) developed on the basis of the natural ecdysterone (20E) contained in various plant sources such as Leuzea carthamoides alias Rhaponticum carthamoides, Rhaponticum integrifolium, Silene brahuica, Ajuga turkestanica etc. by the Institute of the Chemistry of Plant Substances (Tashkent, Republic of Uzbekistan), and the “Ekdifit” preparation developed at the International Research and Production Holding “Phytochemistry” (Karaganda, Republic of Kazakhstan), which is the sum of the extracs of Serratula coronata and contains 20E as the main active component and additional amounts of ecdysteroids and flavonoids [1], [2], [3], [4].

Název v anglickém jazyce

Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

Popis výsledku anglicky

In recent years, the interest in metabolic-type and natural products drugs that have the ability to activate plastic processes in various organs and tissues, improve the energy status of their cellular systems, and thereby improve the body resistance to various adverse factors, increased significantly. According to the results of the experimental and clinical studies, one of the most effective drugs in this area could be “Ecdisten” (Five Stars Laboratory, Bulgaria) developed on the basis of the natural ecdysterone (20E) contained in various plant sources such as Leuzea carthamoides alias Rhaponticum carthamoides, Rhaponticum integrifolium, Silene brahuica, Ajuga turkestanica etc. by the Institute of the Chemistry of Plant Substances (Tashkent, Republic of Uzbekistan), and the “Ekdifit” preparation developed at the International Research and Production Holding “Phytochemistry” (Karaganda, Republic of Kazakhstan), which is the sum of the extracs of Serratula coronata and contains 20E as the main active component and additional amounts of ecdysteroids and flavonoids [1], [2], [3], [4].

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

STEROIDS

ISSN

0039-128X

e-ISSN

—

Svazek periodika

2019

Číslo periodika v rámci svazku

147

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

37-41

Kód UT WoS článku

000487004300007

EID výsledku v databázi Scopus

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