Iodinated Choline Transport-Targeted Tracers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73602636" target="_blank" >RIV/61989592:15110/20:73602636 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389013:_____/20:00536679 RIV/00216208:11310/20:10422520 RIV/60461373:22330/20:43923099

Výsledek na webu

<a href="https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01710" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01710</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.jmedchem.0c01710" target="_blank" >10.1021/acs.jmedchem.0c01710</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Iodinated Choline Transport-Targeted Tracers

Popis výsledku v původním jazyce

Radionuclide imaging methods, such as planar scintigraphy, positron emission tomography (PET), and single-photon emission computed tomography (SPECT), have become invaluable because of their ability to distinguish biochemical changes in tissues (functional imaging) and are routinely used for staging, prognosing, and predicting the therapeutic outcome of many diseases, especially cancer.(1) Plain film radiography, X-ray computed tomography (CT), and magnetic resonance imaging (MRI) can be used to evaluate the anatomical extent of diseases with sub-millimeter resolution. PET and SPECT have lower spatial resolution,(2) but they are able to visualize in vivo biological processes in real time and detect the concentrations of specific biomolecules in the picomolar range.(3) Both PET and SPECT rely on radiolabeled pharmaceuticals, which are used as imaging agents.

Název v anglickém jazyce

Iodinated Choline Transport-Targeted Tracers

Popis výsledku anglicky

Radionuclide imaging methods, such as planar scintigraphy, positron emission tomography (PET), and single-photon emission computed tomography (SPECT), have become invaluable because of their ability to distinguish biochemical changes in tissues (functional imaging) and are routinely used for staging, prognosing, and predicting the therapeutic outcome of many diseases, especially cancer.(1) Plain film radiography, X-ray computed tomography (CT), and magnetic resonance imaging (MRI) can be used to evaluate the anatomical extent of diseases with sub-millimeter resolution. PET and SPECT have lower spatial resolution,(2) but they are able to visualize in vivo biological processes in real time and detect the concentrations of specific biomolecules in the picomolar range.(3) Both PET and SPECT rely on radiolabeled pharmaceuticals, which are used as imaging agents.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF MEDICINAL CHEMISTRY

ISSN

0022-2623

e-ISSN

—

Svazek periodika

63

Číslo periodika v rámci svazku

24

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

19

Strana od-do

15960-15978

Kód UT WoS článku

000603401900045

EID výsledku v databázi Scopus

2-s2.0-85097899954